70369-47-0

• 常用中文名：BUCINDOLOL
• 常用英文名：BUCINDOLOL
• CAS号：70369-47-0
• 分子式：C₂₂H₂₅N₃O₂
• 分子量：363.45300
• 发布时间：2016-02-16 10:37:52
• 更新时间：2024-04-02 11:28:44

名称

• 英文名: 2-[2-hydroxy-3-[[1-(1H-indol-3-yl)-2-methylpropan-2-yl]amino]propoxy]benzonitrile,hydrochloride
• 英文别名: o-(2-Hydroxy-3-((2-indol-3-yl-1,1-dimethylethyl)amino)propoxy)benzonitrile monohydrochloride; Bucindolol HCl; Bucindolol hydrochloride; Benzonitrile,2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)-,monohydrochloride; 2-(2-Hydroxy-3-((2-(3-indolyl)-1,1-dimethylethyl)amino)propoxy)benzonitrile hydrochloride; Bucindolol hydrochloride (USAN)

物化性质

• 沸点: 605.3ºC at 760 mmHg
• 分子式: C₂₂H₂₅N₃O₂
• 分子量: 363.45300
• 闪点: 319.9ºC
• 精确质量: 363.19500
• PSA: 81.07000
• LogP: 3.78108

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DI4605000 CHEMICAL NAME : Benzonitrile, 2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl) amino)propoxy)-, monohydrochloride CAS REGISTRY NUMBER : 70369-47-0 LAST UPDATED : 198910 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C22-H25-N3-O2.Cl-H MOLECULAR WEIGHT : 399.96 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - ataxia REFERENCE : NDADD8 New Drugs Annual: Cardiovascular Drugs. (New York, NY) V.1-2, 1983-84. For publisher information, see NCDREP. Volume(issue)/page/year: 1,1,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - ataxia REFERENCE : NDADD8 New Drugs Annual: Cardiovascular Drugs. (New York, NY) V.1-2, 1983-84. For publisher information, see NCDREP. Volume(issue)/page/year: 1,1,1983