3625-06-7

• 常用中文名：美贝维林
• 常用英文名：Mebeverine
• CAS号：3625-06-7
• 分子式：C₂₅H₃₅NO₅
• 分子量：429.549
• 相关类别： 原料药 消化系统用药 胃肠解痉药
• 发布时间：2018-02-28 08:00:00
• 更新时间：2024-01-19 19:14:48

名称

• 中文名: 美贝维林
• 英文名: 4-[ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butyl 3,4-dimethoxybenzoate
• 英文别名: 4-[N-[2-(p-Methoxyphenyl)-1-methylethyl]-N-ethylamino]butyl 3,4-Dimethoxybenzoate; 3,4-Dimethoxybenzoic Acid 4-[Ethyl(p-methoxy-a-methylphenethyl)amino]butyl Ester; Mebeverine; 4-{Ethyl[1-(4-methoxyphenyl)-2-propanyl]amino}butyl 3,4-dimethoxybenzoate; Mebeverina; Benzoic acid, 3,4-dimethoxy-, {4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]butyl} ester; 4-{ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino}butyl 3,4-dimethoxybenzoate; Benzoic acid, 3,4-dimethoxy-, 4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]butyl ester; 4-(Ethyl(2-(4-methoxyphenyl)-1-methylethyl)amino)butyl 3,4-dimethoxybenzoate; Veratric Acid 4-[Ethyl(p-methoxy-a-methylphenethyl)amino]butyl Ester; 4-(ethyl{1-methyl-2-[4-(methyloxy)phenyl]ethyl}amino)butyl 3,4-bis(methyloxy)benzoate; Mebeverinum; 3,4-Dimethoxybenzoic Acid 4-[Ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]butyl Ester; 4-[Ethyl(p-methoxy-a-methylphenethyl)amino]butyl 3,4-Dimethoxybenzoate; 4-{ethyl[1-(4-methoxyphenyl)propan-2-yl]amino}butyl 3,4-dimethoxybenzoate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 543.8±50.0 °C at 760 mmHg
• 分子式: C₂₅H₃₅NO₅
• 分子量: 429.549
• 闪点: 282.7±30.1 °C
• 精确质量: 429.251526
• PSA: 57.23000
• LogP: 5.60
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.529

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YX5250000 CHEMICAL NAME : Veratric acid, 4-((ethyl(p-methoxy-alpha-methylphenethyl))amino)buty l ester CAS REGISTRY NUMBER : 3625-06-7 LAST UPDATED : 199706 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C25-H35-N-O5 MOLECULAR WEIGHT : 429.61 WISWESSER LINE NOTATION : 1OR BO1 DVO4N2&Y1&1R DO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 995 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 145,378,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 199 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 145,378,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 324 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 145,378,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 24 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 145,378,1963

安全

• 海关编码: 2922509090

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海关

海关编码	2922509090
中文概述	2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%