75176-37-3

• 常用中文名：佐芬普利
• 常用英文名：Zofenoprilat
• CAS号：75176-37-3
• 分子式：C₁₅H₁₉NO₃S₂
• 分子量：325.446
• 发布时间：2018-06-22 18:03:06
• 更新时间：2025-08-26 11:19:49

名称

• 中文名: 佐芬普利
• 英文名: zofenoprilat
• 中文别名: [1(R*),2alpha,4alpha]-1-[3-巯基-2-甲基-1-氧代丙基]-4-(苯硫基)-L-脯氨酸
• 英文别名: Zofenoprilat; (4S)-1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline; L-Proline, 1-[(2R)-3-mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-, (4S)-; [1(S),4(S)]-1-(3-Mercapto-2-methyl-1-oxopropyl)-4-phenyl-thio-L-proline; (2s,4s)-1-[(2r)-2-methyl-3-sulfanyl-propanoyl]-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid; (1(r*),2alpha,4alpha)-1-(3-mercapto-2-methyl-1-oxopropyl)-4-(phenylthio)-l-proline; [1(R*),2a,4a]-1-(3-Mercapto-2-methyl-1-oxopropyl)-4-(phenylthio)-L-proline; (4S)-1-[(2R)-2-Methyl-3-sulfanylpropanoyl]-4-(phenylsulfanyl)-L-proline; (4S)-1-[(2S)-3-mercapto-2-methylpropanoyl]-4-(phenylthio)-L-proline

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 556.2±50.0 °C at 760 mmHg
• 分子式: C₁₅H₁₉NO₃S₂
• 分子量: 325.446
• 闪点: 290.2±30.1 °C
• 精确质量: 325.080627
• PSA: 121.71000
• LogP: 2.14
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.630

合成路线

113949-52-3 ~% 75176-37-3

文献：Journal of Medicinal Chemistry, , vol. 31, # 6 p. 1148 - 1160

80586-33-0 ~% 75176-37-3

文献：Journal of Medicinal Chemistry, , vol. 31, # 6 p. 1148 - 1160

51-35-4 ~% 75176-37-3

文献：Journal of Medicinal Chemistry, , vol. 31, # 6 p. 1148 - 1160

126111-05-5 ~% 75176-37-3

文献：Bioorganic and Medicinal Chemistry, , vol. 12, # 3 p. 603 - 611

81653-77-2 ~% 75176-37-3

文献：Bioorganic and Medicinal Chemistry, , vol. 12, # 3 p. 603 - 611

681144-92-3 ~% 75176-37-3

文献：Bioorganic and Medicinal Chemistry, , vol. 12, # 3 p. 603 - 611

81814-84-8 ~% 75176-37-3

文献：Journal of Medicinal Chemistry, , vol. 31, # 6 p. 1148 - 1160

上下游产品

上游产品  6
113949-52-3 81814-84-8 51-35-4 126111-05-5
81653-77-2 681144-92-3
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