147249-33-0

• 常用中文名：Aspalatone
• 常用英文名：Aspalatone
• CAS号：147249-33-0
• 分子式：C₁₅H₁₂O₆
• 分子量：288.252
• 发布时间：2017-02-02 07:31:29
• 更新时间：2024-01-11 08:45:58
• Aspalatone is an anti-platelet aggregator (antithrombotic) that has been shown to prolong bleeding time in the mouse model. Aspalatone generates antioxidant and neuroprotective effects against kainic acid-induced epilepsy.

名称

• 英文名: (2-methyl-4-oxopyran-3-yl) 2-acetyloxybenzoate
• 英文别名: Aspalatone; 2-Methyl-4-oxo-4H-pyran-3-yl 2-acetoxybenzoate; BK-111; Benzoic acid, 2-(acetyloxy)-, 2-methyl-4-oxo-4H-pyran-3-yl ester; acetyl salicylic acid maltol ester

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 466.1±45.0 °C at 760 mmHg
• 分子式: C₁₅H₁₂O₆
• 分子量: 288.252
• 闪点: 209.0±28.8 °C
• 精确质量: 288.063385
• PSA: 82.81000
• LogP: 1.16
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.579

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DG0936300 CHEMICAL NAME : Benzoic acid, 2-(acetyloxy)-, 2-methyl-4-oxo-4H-pyran-3-yl ester CAS REGISTRY NUMBER : 147249-33-0 LAST UPDATED : 199603 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C15-H12-O6 MOLECULAR WEIGHT : 288.27 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 44,1122,1994

合成路线

50-78-2 ~% 147249-33-0

文献：Han; Suh; Yang; Park; Kang; Kim Arzneimittel-Forschung/Drug Research, 1994 , vol. 44, # 10 p. 1122 - 1126

118-71-8 5538-51-2 ~% 28787-36-2 147249-33-0

文献：Han; Suh; Yang; Park; Kang; Kim Arzneimittel-Forschung/Drug Research, 1994 , vol. 44, # 10 p. 1122 - 1126

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