59443-94-6

• 常用中文名：3-(4-氨基苯基)-3-氧代丙腈
• 常用英文名：3-(4-aminophenyl)-3-oxopropanenitrile
• CAS号：59443-94-6
• 分子式：C₉H₈N₂O
• 分子量：160.17300
• 发布时间：2019-02-16 21:15:30
• 更新时间：2025-10-02 09:07:15

名称

• 中文名: 3-(4-氨基苯基)-3-氧代丙腈
• 英文名: 3-(4-aminophenyl)-3-oxopropanenitrile
• 中文别名: 4-胺基苯甲酰乙腈
• 英文别名: benzenepropanenitrile,4-amino-|A-oxo; (4-Aminobenzoyl)acetonitrile; Acetonitrile,(p-aminobenzoyl)-(6CI,7CI); 2-(4-Aminobenzoyl)acetonitrile; 3-(4-amino-phenyl)-3-oxo-propionitrile; 4-Aminobenzoylacetonitril; p-aminobenzoylacetonitrile

物化性质

• 密度: 1.203g/cm3
• 沸点: 414.1ºC at 760 mmHg
• 熔点: 157-158ºC
• 分子式: C₉H₈N₂O
• 分子量: 160.17300
• 闪点: 204.2ºC
• 精确质量: 160.06400
• PSA: 66.88000
• LogP: 1.94638
• 折射率: 1.592

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DA8333500 CHEMICAL NAME : Benzenepropanenitrile, 4-amino-beta-oxo- CAS REGISTRY NUMBER : 59443-94-6 LAST UPDATED : 199712 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C9-H8-N2-O HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2263 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571038 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1600 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571038 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7332 mg/kg/12D-C TOXIC EFFECTS : Liver - changes in liver weight Endocrine - changes in thyroid weight Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571038

合成路线

2631-71-2 151-50-8 ~% 59443-94-6

文献：Du Pont de Nemours and Co. Patent: US2680730 , 1950 ; Full Text Show Details Eastman Kodak Co. Patent: US2538008 , 1949 ;

103140-29-0 ~% 59443-94-6

文献：Stepanow; Wul'fson Org. Poluprod. Krasit.Chem.Abstr., 1959 , # 1 p. 222,228, 229 Org. Poluprod. Krasit.Chem.Abstr., 1961 , p. 18747

33282-25-6 ~% 59443-94-6

文献：Cusmano; Tiberio Gazzetta Chimica Italiana, 1950 , vol. 80, p. 299,304

5180-75-6 18852-51-2 ~% 59443-94-6

文献：Gen. Aniline and Film Corp. Patent: US2610979 , 1949 ;

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