53-45-2

• 常用中文名：(8R,9S,13S,14S)-13-甲基-7,8,9,11,12,13,15,16-八氢-6H-环戊二烯并[a]菲-17(14H)-酮
• 常用英文名：Estra-1,3,5(10)-trien-17-one
• CAS号：53-45-2
• 分子式：C₁₈H₂₂O
• 分子量：254.36700
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 吡啶衍生物
• 发布时间：2018-03-28 08:00:00
• 更新时间：2024-01-16 23:55:45

名称

• 中文名: 3-脱氧雌素酮
• 英文名: (8R,9S,13S,14S)-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
• 英文别名: Agrestin; Desoxyestrone; estra-1,3,5(10)-trien-17-one; 1,3,5(10)-estratrien-17-one; d-Estra-1,3,5(10)-trien-17-one; Deoxyestrone; 3-Deoxyestrone; 1,3,5(10)-Estratrien-17-one; 3-Deoxyoestrone; Estratrien-17-one; Estrone,3-deoxy; 3-Desoxyestrone; Adopron; Oestra-1,3,5(10)-trien-17-one

物化性质

• 密度: 1.088g/cm3
• 沸点: 387ºC at 760mmHg
• 熔点: 142-144 °C(Experimental)
• 分子式: C₁₈H₂₂O
• 分子量: 254.36700
• 闪点: 167.8ºC
• 精确质量: 254.16700
• PSA: 17.07000
• LogP: 4.11180
• 折射率: 1.565
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KG7744000 CHEMICAL NAME : Estra-1,3,5(10)-trien-17-one CAS REGISTRY NUMBER : 53-45-2 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C18-H22-O MOLECULAR WEIGHT : 254.40 WISWESSER LINE NOTATION : L E5 B666 FVTTT&J E1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 4 mg/kg SEX/DURATION : male 1 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands REFERENCE : ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 49,193,1965