379229-72-8

• 常用中文名：4-氯-5-(四氢-2H-吡喃-4-基氧基)喹唑啉-7-醇
• 常用英文名：4-chloro-5-(oxan-4-yloxy)-3H-quinazolin-7-one
• CAS号：379229-72-8
• 分子式：C₁₃H₁₃ClN₂O₃
• 分子量：280.70700
• 发布时间：2018-12-24 14:37:00
• 更新时间：2025-08-25 09:12:53

名称

• 中文名: 4-氯-5-(四氢-2H-吡喃-4-基氧基)喹唑啉-7-醇
• 英文名: 4-chloro-5-(oxan-4-yloxy)-3H-quinazolin-7-one
• 英文别名: 4-chloro-7-hydroxy-5-tetrahydropyran-4-yloxyquinazoline; 4-chloro-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-7-ol; 7-Quinazolinol,4-chloro-5-[(tetrahydro-2H-pyran-4-yl)oxy]

物化性质

• 分子式: C₁₃H₁₃ClN₂O₃
• 分子量: 280.70700
• 精确质量: 280.06100
• PSA: 64.21000
• LogP: 2.13430

合成路线

379229-33-1 ~% 379229-72-8

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

379229-95-5 ~78% 379229-72-8

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

379228-50-9 ~% 379229-72-8

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

379228-27-0 ~% 379229-72-8

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

379228-51-0 ~% 379229-72-8

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

379229-70-6 ~% 379229-72-8

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

379229-71-7 ~% 379229-72-8

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

21577-57-1 ~% 379229-72-8

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

379228-26-9 ~% 379229-72-8

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

上下游产品

上游产品  9
379229-33-1 379229-95-5 379228-50-9 379228-27-0
379228-51-0 379229-70-6 379229-71-7 21577-57-1
379228-26-9
下游产品  0