379228-48-5

• 常用中文名：4-氯-7-甲氧基-5-[(1-甲基哌啶-4-基)氧基]喹唑啉
• 常用英文名：4-chloro-7-methoxy-5-(1-methylpiperidin-4-yl)oxyquinazoline
• CAS号：379228-48-5
• 分子式：C₁₅H₁₈ClN₃O₂
• 分子量：307.77500
• 发布时间：2018-12-09 08:30:57
• 更新时间：2025-08-25 20:02:46

名称

• 中文名: 4-氯-7-甲氧基-5-[(1-甲基哌啶-4-基)氧基]喹唑啉
• 英文名: 4-chloro-7-methoxy-5-(1-methylpiperidin-4-yl)oxyquinazoline
• 英文别名: 4-chloro-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazoline; 4-chloro-7-methoxy-5-(N-methylpiperidin-4-yloxy)quinazoline; Quinazoline,4-chloro-7-methoxy-5-[(1-methyl-4-piperidinyl)oxy]

物化性质

• 分子式: C₁₅H₁₈ClN₃O₂
• 分子量: 307.77500
• 精确质量: 307.10900
• PSA: 47.48000
• LogP: 2.70270

合成路线

379228-53-2 ~71% 379228-48-5

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

379228-27-0 ~% 379228-50-9 379228-48-5

文献：AstraZeneca AB Patent: EP1292594 B1, 2004 ;

379228-52-1 ~% 379228-48-5

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

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379228-53-2 379228-27-0 379228-52-1
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