660432-17-7

• 常用中文名：1-(2-amino-3-propan-2-ylsulfonylbenzimidazol-5-yl)-2-phenylethane-1,2-dione
• 常用英文名：1-(2-amino-3-propan-2-ylsulfonylbenzimidazol-5-yl)-2-phenylethane-1,2-dione
• CAS号：660432-17-7
• 分子式：C₁₈H₁₇N₃O₄S
• 分子量：371.41000
• 发布时间：2017-09-17 09:30:09
• 更新时间：2025-08-25 22:20:13

名称

• 英文名: 1-(2-amino-3-propan-2-ylsulfonylbenzimidazol-5-yl)-2-phenylethane-1,2-dione
• 英文别名: 1-[2-amino-3-(propane-2-sulfonyl)-3H-benzoimidazol-5-yl]-2-phenyl-ethane-1,2-dione; 1-[2-amino-3-(propane-2-sulfonyl)-3H-benzimidazol-5-yl]-2-phenylethane-1,2-dione; 1,2-ETHANEDIONE,1-[2-AMINO-1-[(1-METHYLETHYL)SULFONYL]-1H-BENZIMIDAZOL-6-YL]-2-PHENYL; 1-isopropylsulfonyl-2-amino-6-(2-phenyl-ethane-1,2-dione)-benzimidazole; 1-isopropylsulfonyl-2-amino-6-(diketo-(2-phenyl)ethyl)-benzimidazole

物化性质

• 分子式: C₁₈H₁₇N₃O₄S
• 分子量: 371.41000
• 精确质量: 371.09400
• PSA: 121.23000
• LogP: 3.28130

合成路线

660432-15-5 ~80% 660432-17-7

文献：ELI LILLY AND COMPANY Patent: WO2004/14900 A1, 2004 ; Location in patent: Page 35-36 ; WO 2004/014900 A1

660432-14-4 ~83% 660432-17-7

文献：Magnus, Nicholas A.; Diseroad, William D.; Nevill Jr., C. Richard; Wepsiec, James P. Organic Process Research and Development, 2006 , vol. 10, # 3 p. 556 - 560

536-74-3 ~% 660432-17-7

文献：De Dios, Alfonso; Shih, Chuan; Lopez De Uralde, Beatriz; Sanchez, Concepcion; Del Prado, Miriam; Martin Cabrejas, Luisa M.; Pleite, Sehila; Blanco-Urgoiti, Jaime; Lorite, Maria Jose; Nevill Jr., C. Richard; Bonjouklian, Rosanne; York, Jeremy; Vieth, Michal; Wang, Yong; Magnus, Nicholas; Campbell, Robert M.; Anderson, Bryan D.; McCann, Denis J.; Giera, Deborah D.; Lee, Paul A.; Schultz, Richard M.; Li, Li C.; Johnson, Lea M.; Wolos, Jeffrey A. Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2270 - 2273

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