31879-05-7

• 常用中文名：菲诺洛芬
• 常用英文名：calcium(-1) anion; 2-(3-phenoxyphenyl)propanoate
• CAS号：31879-05-7
• 分子式：C₁₅H₁₄O₃
• 分子量：522.604
• 相关类别： 原料药 解热镇痛药 非甾抗炎药
• 发布时间：2018-02-17 08:00:00
• 更新时间：2025-08-20 19:13:55

名称

• 中文名: 菲诺洛芬
• 英文名: fenoprofen
• 中文别名: 2-(3-苯氧苯基)丙酸; 苯氧布洛芬
• 英文别名: 2-(3-Phennoxyphenyl)propanoicacid; EINECS 250-850-3; Fenopolfen; (+-)-m-phenoxyhydrotropicacid; dl-2-(3-phenoxyphenyl)propionicacid; FENOPROFEN; (.+/-.)-m-Phenoxyhydratropic acid; MFCD00072027; 2-(3-Phenoxyphenyl)propanoic acid; a-Methyl-3-phenoxybenzeneaceticacid

物化性质

• 密度: 1.183 g/cm3
• 沸点: 168-171ºC at 0.11 MM HG
• 分子式: C₁₅H₁₄O₃
• 分子量: 522.604
• 闪点: 141.7ºC
• 精确质量: 522.137146
• PSA: 46.53000
• LogP: 3.66700

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MU6646000 CHEMICAL NAME : Hydratropic acid, m-phenoxy-, (+-)- CAS REGISTRY NUMBER : 31879-05-7 LAST UPDATED : 199612 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C15-H14-O3 MOLECULAR WEIGHT : 242.29 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human DOSE/DURATION : 4286 ug/kg TOXIC EFFECTS : Endocrine - evidence of thyroid hyperfunction REFERENCE : BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 292,1560,1986 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 1092 mg/kg/13W-I TOXIC EFFECTS : Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - interstitial nephritis Kidney, Ureter, Bladder - other changes REFERENCE : MACPAJ Mayo Clinic Proceedings. (Room 1035, Plummer Bldg., Mayo Clinic, Rochester, MN 55905) V.39- 1964- Volume(issue)/page/year: 55,103,1980 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 9386 mg/kg/1Y-I TOXIC EFFECTS : Kidney, Ureter, Bladder - interstitial nephritis REFERENCE : NEJMAG New England Journal of Medicine. (Massachusetts Medical Soc., 10 Shattuck St., Boston, MA 02115) V.198- 1928- Volume(issue)/page/year: 301,1271,1979 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >200 mg/kg TOXIC EFFECTS : Gastrointestinal - ulceration or bleeding from stomach REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 52,454,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3985779 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 50 mg/kg/4D-I TOXIC EFFECTS : Gastrointestinal - ulceration or bleeding from stomach REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 52,454,1980

安全

• 海关编码: 2918990090

海关

海关编码	2918990090
中文概述	2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%