68677-06-5

• 常用中文名：氯拉必利
• 常用英文名：lorapride
• CAS号：68677-06-5
• 分子式：C₁₄H₂₂ClN₃O₃S
• 分子量：347.86100
• 发布时间：2018-07-14 15:55:24
• 更新时间：2024-01-09 20:37:40

名称

• 中文名: 氯拉必利
• 英文名: 4-amino-5-chloro-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzenesulfonamide
• 中文别名: 若那普瑞
• 英文别名: Lorapride; 4-Amino-5-chloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzenesulfonamide; EINECS 272-057-1; Lorapridum [INN-Latin]; Benzenesulfonamide,4-amino-5-chloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy; Loraprida [INN-Spanish]; 5-Chloro-N(sup 1)-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxysulfanilamide; 5-chloro-n1-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxysulfanilamide

物化性质

• 密度: 1.28g/cm3
• 沸点: 507.5ºC at 760 mmHg
• 分子式: C₁₄H₂₂ClN₃O₃S
• 分子量: 347.86100
• 闪点: 260.7ºC
• 精确质量: 347.10700
• PSA: 93.04000
• LogP: 3.68420
• 折射率: 1.563

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DA9465480 CHEMICAL NAME : Benzenesulfonamide, 4-amino-5-chloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2 -methoxy- CAS REGISTRY NUMBER : 68677-06-5 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C14-H22-Cl-N3-O3-S MOLECULAR WEIGHT : 347.90 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4225611 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4225611 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 130 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4225611