41945-37-3

• 常用中文名：3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine
• 常用英文名：3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine
• CAS号：41945-37-3
• 分子式：C₈H₈BrN₃
• 分子量：226.07300
• 发布时间：2016-08-12 12:10:29
• 更新时间：2025-10-27 17:13:09

名称

• 英文名: 3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine
• 英文别名: 3-Brom-5,7-dimethyl-pyrazolo<1,5-a>pyrimidin; Pyrazolo(1,5-a)pyrimidine,3-bromo-5,7-dimethyl; 3-bromo5,7-dimethylpyrazolo[1,5-a]pyrimidine

物化性质

• 密度: 1.67g/cm3
• 分子式: C₈H₈BrN₃
• 分子量: 226.07300
• 精确质量: 224.99000
• PSA: 30.19000
• LogP: 2.10860
• 折射率: 1.687

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UR0720000 CHEMICAL NAME : Pyrazolo(1,5-a)pyrimidine, 3-bromo-5,7-dimethyl- CAS REGISTRY NUMBER : 41945-37-3 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C8-H8-Br-N3 MOLECULAR WEIGHT : 226.10 WISWESSER LINE NOTATION : T56 ANN FNJ DE G1 I1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1346 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,386,1977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 458 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,386,1977

合成路线

128-08-5 35149-38-3 ~57% 41945-37-3

文献：ICN Pharmaceuticals, Inc. Patent: US4093617 A1, 1978 ; US 4093617 A