264208-72-2

• 常用中文名：4-氯-6-甲氧基-7-[(1-甲基-4-哌啶基)甲氧基]-喹唑烷
• 常用英文名：4-chloro-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline
• CAS号：264208-72-2
• 分子式：C₁₆H₂₀ClN₃O₂
• 分子量：321.80200
• 发布时间：2018-11-23 14:07:48
• 更新时间：2026-07-16 15:02:21

名称

• 中文名: 4-氯-6-甲氧基-7-[(1-甲基-4-哌啶基)甲氧基]-喹唑烷
• 英文名: 4-chloro-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline
• 中文别名: 4-氯-6-甲氧基-7-((1-甲基哌啶-4-基)甲氧基)喹唑啉; 凡德他尼中间体-B; 4-氯-6-甲氧基-7-(4 - 甲基哌啶1-甲氧基)喹唑啉; 4-氯-7-[N-甲基哌啶-4-基甲氧基]-6-甲氧基喹唑啉
• 英文别名: 4-Chloro-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline; Vandetanib Impurity 1; 4-Chloro-6-Methoxy-7-(4-Methyl-piperidin-1-ylMethoxy)-quinazoline; 4-Chloro-7-[N-methylpiperidin-4-ylmethoxy]-6-methoxyquinazoline; 7-((1-Methylpiperidin-4-yl)Methoxy)-4-chloro-6-Methoxyquinazoline; 4-chloro-6-Methoxy-7-[(1-Methyl-4-piperidinyl)Methoxy]-Quinazoline; Quinazoline,4-chloro-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]

物化性质

• 分子式: C₁₆H₂₀ClN₃O₂
• 分子量: 321.80200
• 精确质量: 321.12400
• PSA: 47.48000
• LogP: 2.95030

安全

• 海关编码: 2933990090

合成路线

264208-69-7 ~95% 264208-72-2

文献：AstraZeneca AB Patent: EP1119567 B1, 2005 ; Location in patent: Page/Page column 36 ;

123855-51-6 ~% 264208-72-2

文献：Hennequin, Laurent F.; Stokes, Elaine S. E.; Thomas, Andrew P.; Johnstone, Craig; Ple, Patrick A.; Ogilvie, Donald J.; Dukes, Michael; Wedge, Stephen R.; Kendrew, Jane; Curwen, Jon O. Journal of Medicinal Chemistry, 2002 , vol. 45, # 6 p. 1300 - 1312

3943-74-6 ~% 264208-72-2

文献：Seimbille, Yann; Phelps, Michael E.; Czernin, Johannes; Silverman, Daniel H. S. Journal of Labelled Compounds and Radiopharmaceuticals, 2005 , vol. 48, # 11 p. 829 - 843

635678-09-0 ~% 264208-72-2

文献：Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 48, # 11 p. 829 - 843

906565-53-5 ~% 264208-72-2

文献：Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 48, # 11 p. 829 - 843

906565-52-4 ~% 264208-72-2

文献：Seimbille, Yann; Phelps, Michael E.; Czernin, Johannes; Silverman, Daniel H. S. Journal of Labelled Compounds and Radiopharmaceuticals, 2005 , vol. 48, # 11 p. 829 - 843

193002-25-4 ~% 264208-72-2

文献：Hennequin, Laurent F.; Stokes, Elaine S. E.; Thomas, Andrew P.; Johnstone, Craig; Ple, Patrick A.; Ogilvie, Donald J.; Dukes, Michael; Wedge, Stephen R.; Kendrew, Jane; Curwen, Jon O. Journal of Medicinal Chemistry, 2002 , vol. 45, # 6 p. 1300 - 1312

264208-86-8 ~% 264208-72-2

文献：Hennequin, Laurent F.; Stokes, Elaine S. E.; Thomas, Andrew P.; Johnstone, Craig; Ple, Patrick A.; Ogilvie, Donald J.; Dukes, Michael; Wedge, Stephen R.; Kendrew, Jane; Curwen, Jon O. Journal of Medicinal Chemistry, 2002 , vol. 45, # 6 p. 1300 - 1312

20691-89-8 ~% 264208-72-2

文献：Yu, Bing; Tang, Li-Da; Li, Yi-Liang; Song, Shu-Hui; Ji, Xiao-Liang; Lin, Mu-Sen; Wu, Chun-Fu Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 110 - 114

上下游产品

上游产品  8
264208-69-7 123855-51-6 3943-74-6 635678-09-0
906565-52-4 193002-25-4 264208-86-8 20691-89-8
下游产品  1
443913-73-3

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%