27463-04-3

• 常用中文名：2-Hydroxy-1-(2-methyl-1H-indol-3-yl)ethanone
• 常用英文名：2-Hydroxy-1-(2-methyl-1H-indol-3-yl)ethanone
• CAS号：27463-04-3
• 分子式：C₁₁H₁₁NO₂
• 分子量：189.21100
• 发布时间：2017-04-24 17:50:59
• 更新时间：2024-01-28 08:57:19

名称

• 英文名: 2-Hydroxy-1-(2-methyl-1H-indol-3-yl)ethanone
• 英文别名: Indole,3-(hydroxyacetyl)-2-methyl; 3-(2-Hydroxyacetyl)-2-methylindole; 2-hydroxy-1-(2-methyl-indol-3-yl)-ethanone; 2-Methyl-3-hydroxyacetyl-indol; KETONE,HYDROXYMETHYL 2-METHYL-3-INDOLYL; 2-Hydroxy-1-(2-methyl-indol-3-yl)-aethanon

物化性质

• 密度: 1.285g/cm3
• 沸点: 400.1ºC at 760mmHg
• 分子式: C₁₁H₁₁NO₂
• 分子量: 189.21100
• 闪点: 195.8ºC
• 精确质量: 189.07900
• PSA: 53.09000
• LogP: 1.65130
• 蒸汽压: 4.05E-07mmHg at 25°C
• 折射率: 1.669

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OB4356600 CHEMICAL NAME : Ketone, hydroxymethyl 2-methyl-3-indolyl CAS REGISTRY NUMBER : 27463-04-3 BEILSTEIN REFERENCE NO. : 0142720 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C11-H11-N-O2 MOLECULAR WEIGHT : 189.23 WISWESSER LINE NOTATION : T56 BMJ C1 DV1Q HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Behavioral - anticonvulsant Behavioral - changes in motor activity (specific assay) REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 6,33,1972

合成路线

38693-08-2 ~% 27463-04-3

文献：Mingoia Gazzetta Chimica Italiana, 1929 , vol. 59, p. 113

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