339-16-2

• 常用中文名：all-trans-Retinoic Acid Methyl Ester
• 常用英文名：Retinoic acid, methyl ester
• CAS号：339-16-2
• 分子式：C₂₁H₃₀O₂
• 分子量：314.46200
• 发布时间：2016-03-25 00:25:04
• 更新时间：2025-08-27 10:19:31

名称

• 中文名: all-trans-Retinoic Acid Methyl Ester
• 英文名: methyl (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoate
• 英文别名: Vitamin A acid methyl ester; Retinoic acid,methyl ester,all-trans; all-trans-Methylretinoate; Methyl retinoate; Ro 4-3781; all-trans-retinoic acid methyl ester; Retinoic acid,methyl ester; Methyl all-trans-retinoate

物化性质

• 密度: 0.975g/cm3
• 沸点: 426.1ºC at 760mmHg
• 熔点: 66-68 °C
• 分子式: C₂₁H₃₀O₂
• 分子量: 314.46200
• 闪点: 229.8ºC
• 精确质量: 314.22500
• PSA: 26.30000
• LogP: 5.69100
• 折射率: 1.534
• 储存条件: -20°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VH6570000 CHEMICAL NAME : Retinoic acid, methyl ester CAS REGISTRY NUMBER : 339-16-2 BEILSTEIN REFERENCE NO. : 2059353 LAST UPDATED : 199703 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H30-O2 MOLECULAR WEIGHT : 314.51 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2128462 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 18,213,1984

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