80841-48-1

• 常用中文名：ETHANESULFONIC ACID, 2-HYDROXY-, compounded eith 9-((2-METHOXY-4-((METHYLSULFONYL)AMINO)PHENYL)AMINO)-N,5-DIMETHYL-4-ACRIDINECARBOXAMIDE (1:1)
• 常用英文名：ETHANESULFONIC ACID, 2-HYDROXY-, compounded eith 9-((2-METHOXY-4-((METHYLSULFONYL)AMINO)PHENYL)AMINO)-N,5-DIMETHYL-4-ACRIDINECARBOXAMIDE (1:1)
• CAS号：80841-48-1
• 分子式：C₂₆H₃₀N₄O₈S₂
• 分子量：590.66800
• 发布时间：2016-03-07 09:28:48
• 更新时间：2025-10-02 20:43:45

名称

• 英文名: 2-hydroxyethanesulfonic acid,9-[4-(methanesulfonamido)-2-methoxyanilino]-N,5-dimethylacridine-4-carboxamide
• 英文别名: Ci-921; Amsalog; Asulacrine isethionate

物化性质

• 沸点: 861.2ºC at 760 mmHg
• 分子式: C₂₆H₃₀N₄O₈S₂
• 分子量: 590.66800
• 闪点: 474.6ºC
• 精确质量: 590.15100
• PSA: 200.78000
• LogP: 5.74470

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KI7951000 CAS REGISTRY NUMBER : 80841-48-1 LAST UPDATED : 199709 DATA ITEMS CITED : 10 MOLECULAR FORMULA : C2-H6-O4-S.C24-H24-N4-O4-S MOLECULAR WEIGHT : 590.72 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous DOSE : 10 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous DOSE : 26 mg/kg SEX/DURATION : female 6-18 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) MUTATION DATA TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 250 nmol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 204,207,1988

合成路线

107-36-8 80841-47-0 ~92% 80841-48-1

文献：Brennan; Colbry; Leeds; Leja; Priebe; Reily; Showalter; Uhlendorf; Atwell; Denny Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 5 p. 1469 - 1476

92138-15-3 ~% 80841-48-1

文献：Denny; Atwell; Baguley Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 363 - 367

57165-06-7 88915-00-8 ~% 80841-48-1

文献：Denny; Atwell; Baguley Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 363 - 367

上下游产品

上游产品  5
107-36-8 80841-47-0 92138-15-3 57165-06-7
88915-00-8
下游产品  0