3690-04-8

• 常用中文名：氨丙吡酮
• 常用英文名：AMINOPROPYLON
• CAS号：3690-04-8
• 分子式：C₁₆H₂₂N₄O₂
• 分子量：302.37100
• 发布时间：2018-06-02 08:00:00
• 更新时间：2025-08-23 11:41:24

名称

• 中文名: 氨丙吡酮
• 英文名: 2-(dimethylamino)-N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)propanamide
• 英文别名: Aminopropylon; EINECS 222-999-4; PK 3 (pharmaceutical); Aminopropylone; Mipylo; N,N-Dimethyl-DL-alanine-4-antipyrineamide; 4-<2-Dimethylamino-propionylamino>-antipyrin; N,N-Dimethyl-DL-alanin-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylamid); N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-2-(dimethylamino)-propanamide; 4-(2-(Dimethylamino)propionamido)antipyrine; amipylo; N,N-dimethyl-DL-alanine 1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylamide; N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-2-(dimethylamino)propionamide

物化性质

• 密度: 1.2g/cm3
• 分子式: C₁₆H₂₂N₄O₂
• 分子量: 302.37100
• 精确质量: 302.17400
• PSA: 59.27000
• LogP: 1.44600
• 折射率: 1.603
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UE3090300 CHEMICAL NAME : Propionamide, N-antipyrinyl-2-(dimethylamino)- CAS REGISTRY NUMBER : 3690-04-8 BEILSTEIN REFERENCE NO. : 0038137 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C16-H22-N4-O2 MOLECULAR WEIGHT : 302.42 WISWESSER LINE NOTATION : T5NNVJ A1 BR& DMVY1&N1&1 E1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2950 mg/kg TOXIC EFFECTS : Behavioral - analgesia REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 13,109,1977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 820 mg/kg TOXIC EFFECTS : Behavioral - analgesia REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 13,109,1977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1970 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 37,185,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2120 mg/kg TOXIC EFFECTS : Behavioral - analgesia REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 13,109,1977

合成路线

83-07-8 ~% 3690-04-8

文献：Yakugaku Zasshi, , vol. 72, p. 614 Chem.Abstr., , p. 6406

130515-23-0 83-07-8 ~% 3690-04-8

文献：Yakugaku Zasshi, , vol. 75, p. 1431,1432 Chem.Abstr., , p. 10086

82614-49-1 83-07-8 ~% 3690-04-8

文献：Yakugaku Zasshi, , vol. 75, p. 1431,1432 Chem.Abstr., , p. 10086

92296-04-3 124-40-3 ~% 3690-04-8

文献：Yakugaku Zasshi, , vol. 72, p. 614 Chem.Abstr., , p. 6406

101937-73-9 124-40-3 ~% 3690-04-8

文献：Yakugaku Zasshi, , vol. 75, p. 1431,1432 Chem.Abstr., , p. 10086

83-07-8 124-40-3 598-72-1 ~% 3690-04-8

文献：Yakugaku Zasshi, , vol. 75, p. 1431,1432 Chem.Abstr., , p. 10086

上下游产品

上游产品  6
83-07-8 130515-23-0 82614-49-1 124-40-3
101937-73-9 598-72-1
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