75696-02-5

• 常用中文名：西诺西泮
• 常用英文名：Cinolazepam
• CAS号：75696-02-5
• 分子式：C₁₈H₁₃ClFN₃O₂
• 分子量：357.76600
• 发布时间：2018-02-20 08:00:00
• 更新时间：2024-01-08 21:15:15
• Cinolazepam is a benzodiazepine derivative drug. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Due to its strong sedative properties, it is primarily used as an hypnotic.

名称

• 中文名: 西诺西泮
• 英文名: cinolazepam
• 英文别名: OX-373; 3-[7-chloro-5-(2-fluorophenyl)-3-hydroxy-2-oxo-3H-1,4-benzodiazepin-1-yl]propanenitrile; Cinolazepam; Cinolazepamum [INN-Latin]; Cinolazepam [INN]; Gerodorm; Gerodorm (TN); Cinolazepamum

物化性质

• 密度: 1.39g/cm3
• 沸点: 643.5ºC at 760 mmHg
• 分子式: C₁₈H₁₃ClFN₃O₂
• 分子量: 357.76600
• 闪点: 343ºC
• 精确质量: 357.06800
• PSA: 76.69000
• LogP: 2.39578
• 折射率: 1.646

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DE9640000 CHEMICAL NAME : 1H-1,4-Benzodiazepine-1-propanenitrile, 2,3-dihydro-7-chloro-5-(2-fluorophenyl)-2-oxo- CAS REGISTRY NUMBER : 75696-02-5 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C18-H13-Cl-F-N3-O2 MOLECULAR WEIGHT : 357.79 WISWESSER LINE NOTATION : T67 GNV JN IHJ CG G2CN IQ KR BF HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,98,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,98,1982