467-36-7

• 常用中文名：硫烯比妥
• 常用英文名：thialbarbital
• CAS号：467-36-7
• 分子式：C₁₃H₁₆N₂O₂S
• 分子量：264.34300
• 发布时间：2018-05-10 08:00:00
• 更新时间：2025-08-25 19:54:26

名称

• 中文名: 硫烯比妥
• 英文名: 5-cyclohex-2-en-1-yl-5-prop-2-enyl-2-sulfanylidene-1,3-diazinane-4,6-dione
• 英文别名: Tialbarbitale [DCIT]; 5-allyl-5-cyclohex-2-enyl-2-thioxo-dihydro-pyrimidine-4,6-dione; Thialpenton; 5-Allyl-5-cyclohex-2-enyl-2-thio-barbitursaeure; Thialbarbitalum [INN-Latin]; Thialbarbital; Tialbarbital [INN-Spanish]; Thialbarbitone; 4,6(1H,5H)-Pyrimidinedione,5-(2-cyclohexen-1-yl)dihydro-5-(2-propenyl)-2-thioxo; Thialbital,5-Allyl-5-<cyclohexen-(2)-yl>-2-thio-barbitursaeure; Kemithal; Thiohexallymalum; 5-allyl-5-cyclohex-2-enyl-2-thio-barbituric acid; EINECS 207-390-3

物化性质

• 密度: 1.25g/cm3
• 分子式: C₁₃H₁₆N₂O₂S
• 分子量: 264.34300
• 精确质量: 264.09300
• PSA: 97.27000
• LogP: 1.98790
• 折射率: 1.606

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CP8400000 CHEMICAL NAME : Barbituric acid, 5-allyl-5-(2-cyclohexen-1-yl)-2-thio- CAS REGISTRY NUMBER : 467-36-7 LAST UPDATED : 199007 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C13-H16-N2-O2-S MOLECULAR WEIGHT : 264.37 WISWESSER LINE NOTATION : T6VMYMV FHJ CUS F2U1 F- CL6UTJ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 175 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 106,437,1956 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 370 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 1,215,1946 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 384 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 1,215,1946 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 240 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FSTEAI Farmaco. Scienza e Tecnica. (Pavia, Italy) V.1-7, 1946-52. For publisher information, see FRPSAX. Volume(issue)/page/year: 3,269,1948 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 390 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 1,215,1946

合成路线

17356-08-0 ~% 467-36-7

文献：Abe Yakugaku Zasshi, 1955 , vol. 75, p. 885 Chem.Abstr., 1956 , p. 4978