123258-84-4

• 常用中文名：N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-3H-benzimidazole-1-carboxamide
• 常用英文名：N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-3H-benzimidazole-1-carboxamide
• CAS号：123258-84-4
• 分子式：C₁₆H₂₀N₄O₂
• 分子量：300.35600
• 发布时间：2016-02-15 14:29:54
• 更新时间：2025-08-26 11:55:01

名称

• 英文名: N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-3H-benzimidazole-1-carboxamide
• 英文别名: N-(endo-8-methyl-8-azabicyclo[3,2,1]oct-3-yl)-2,3-dihydro-2-oxo-1H-benzimidazol-1-carboxamide; N-(endo-8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxamide; Itasetron [USAN:INN]; endo-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxamide; DAU6215CL; ITASETRON

物化性质

• 密度: 1.35g/cm3
• 分子式: C₁₆H₂₀N₄O₂
• 分子量: 300.35600
• 精确质量: 300.15900
• PSA: 73.88000
• LogP: 2.06710
• 折射率: 1.664

合成路线

87571-88-8 65657-53-6 ~73% 123258-84-4

文献：Turconi, Marco; Nicola, Massimo; Quintero, Myrna Gil; Maiocchi, Luciano; Micheletti, Rosella; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2101 - 2108

615-16-7 ~% 123258-84-4

文献：Turconi, Marco; Nicola, Massimo; Quintero, Myrna Gil; Maiocchi, Luciano; Micheletti, Rosella; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2101 - 2108