34580-70-6

• 常用中文名：3-(2-piperidin-1-ylethoxy)-1-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-b]pyridine,hydrochloride
• 常用英文名：3-(2-piperidin-1-ylethoxy)-1-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-b]pyridine,hydrochloride
• CAS号：34580-70-6
• 分子式：C₂₀H₂₂ClF₃N₄O
• 分子量：426.86300
• 发布时间：2016-07-30 00:57:44
• 更新时间：2025-09-30 17:46:58

名称

• 英文名: 3-(2-piperidin-1-ylethoxy)-1-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-b]pyridine,hydrochloride
• 英文别名: itf 1018

物化性质

• 沸点: 453.7ºC at 760 mmHg
• 分子式: C₂₀H₂₂ClF₃N₄O
• 分子量: 426.86300
• 闪点: 228.2ºC
• 精确质量: 426.14300
• PSA: 43.18000
• LogP: 5.04390

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UR0711600 CHEMICAL NAME : 1H-Pyrazolo(3,4-b)pyridine, 3-(2-(1-piperidinyl)ethoxy)-1-(3-(trifluoromethyl)phe nyl)-, monohydrochloride CAS REGISTRY NUMBER : 34580-70-6 LAST UPDATED : 199203 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C20-H21-F3-N4-O.Cl-H MOLECULAR WEIGHT : 426.91 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972