226398-50-1

• 常用中文名：4-[(4-氟苯基)磺酰基]-1-哌啶甲酸叔丁酯
• 常用英文名：4-(4-Fluoro-benzenesulfonyl)-piperidine-1-carboxylicacidtert-butylester
• CAS号：226398-50-1
• 分子式：C₁₆H₂₂FNO₄S
• 分子量：343.41400
• 发布时间：2018-12-24 14:01:09
• 更新时间：2024-01-08 16:13:37

名称

• 中文名: 4-(4-氟苯磺酰基)-哌啶-1-羧酸叔丁酯
• 英文名: tert-butyl 4-(4-fluorophenyl)sulfonylpiperidine-1-carboxylate
• 英文别名: tert-butyl 4-[(4-fluorophenyl)sulfonyl]piperidine-1-carboxylate; tert-butyl 4-(4-fluoro-benzenesulfonyl)-piperidine-1-carboxylate; N-BOC 4-(4-fluorophenylsulfonyl)piperidine; N-tert-butoxycarbonyl-4-(4-fluorophenylsulfonyl)piperidine; 1-tert-Butoxycarbonyl-4-(4-fluorophenylsulfonyl)piperidine; tert-butyl 4-[(4-fluorophenyl)sulfonyl]piperidinecarboxylate; 4-(4-FLUORO-BENZENESULFONYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

物化性质

• 密度: 1.243 g/cm3
• 沸点: 473.6±45.0 °C(Predicted)
• 熔点: 167-169 °C
• 分子式: C₁₆H₂₂FNO₄S
• 分子量: 343.41400
• 精确质量: 343.12500
• PSA: 72.06000
• LogP: 4.01760
• 储存条件: 2-8°C， 密封

安全

• 海关编码: 2933399090

合成路线

226398-48-7 ~91% 226398-50-1

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2007/106705 A1, 2007 ; Location in patent: Page/Page column 86 ; WO 2007/106705 A1

109384-19-2 ~% 226398-50-1

文献：Fletcher, Stephen R.; Burkamp, Frank; Blurton, Peter; Cheng, Susan K. F.; Clarkson, Robert; O'Connor, Desmond; Spinks, Daniel; Tudge, Matthew; Van Niel, Monique B.; Patel, Smita; Chapman, Kerry; Marwood, Rose; Shepheard, Sara; Bentley, Graham; Cook, Gina P.; Bristow, Linda J.; Castro, Jose L.; Hutson, Peter H.; MacLeod, Angus M. Journal of Medicinal Chemistry, 2002 , vol. 45, # 2 p. 492 - 503

141699-59-4 ~% 226398-50-1

文献：Imamura, Shinichi; Ichikawa, Takashi; Nishikawa, Youichi; Kanzaki, Naoyuki; Takashima, Katsunori; Niwa, Shinichi; Iizawa, Yuji; Baba, Masanori; Sugihara, Yoshihiro Journal of Medicinal Chemistry, 2006 , vol. 49, # 9 p. 2784 - 2793

405-31-2 ~% 226398-50-1

文献：Fletcher, Stephen R.; Burkamp, Frank; Blurton, Peter; Cheng, Susan K. F.; Clarkson, Robert; O'Connor, Desmond; Spinks, Daniel; Tudge, Matthew; Van Niel, Monique B.; Patel, Smita; Chapman, Kerry; Marwood, Rose; Shepheard, Sara; Bentley, Graham; Cook, Gina P.; Bristow, Linda J.; Castro, Jose L.; Hutson, Peter H.; MacLeod, Angus M. Journal of Medicinal Chemistry, 2002 , vol. 45, # 2 p. 492 - 503

上下游产品

上游产品  4
226398-48-7 109384-19-2 141699-59-4 405-31-2
下游产品  1
150221-22-0

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%