189028-95-3

• 常用中文名：(4S)-3-[(5S)-5-(4-氟苯基)-5-羟基戊酰基]-4-苯基-1,3-氧氮杂环戊烷-2-酮
• 常用英文名：(4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE
• CAS号：189028-95-3
• 分子式：C₂₀H₂₀FNO₄
• 分子量：357.375
• 发布时间：2018-12-25 15:59:51
• 更新时间：2025-08-25 12:50:27

名称

• 中文名: (4S)-3-[(5S)-5-(4-氟苯基)-5-羟基戊酰基]-4-苯基-1,3-氧氮杂环戊烷-2-酮
• 英文名: (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
• 中文别名: 依替米贝中间体D; (4S)-3-[(5S)-5-(4-氟苯基)-5-羟基-1-氧代戊基]-4-苯基-2-嗯唑烷酮; 依折麦布中间体1; (4S)-3-((5S)-5-(4-氟苯基)-5-羟基戊酰基)-4-苯基-1,3-氧氮杂环戊烷n-2-酮; (4S)-3-[(5s)-5-(4-氟苯基)-5-羟基戊酰基]-4-苯基-1,3-噁唑啉-2-酮; 依折麦布中间体A
• 英文别名: 3-[5-(p-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone; Ezetimibe Intermediate-6; (S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one; 3-[(5S)-(4-fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one; (4S)-phenyl-3-[(5S)-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one; (4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one; 2-Oxazolidinone, 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, (4S)-; (4S)-4-phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one; (S)-3-[5-(4-fluorophenyl)-5(S)-hydroxy-pentanoyl]-4-phenyl-oxazolidin-2-one; (4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 572.7±50.0 °C at 760 mmHg
• 分子式: C₂₀H₂₀FNO₄
• 分子量: 357.375
• 闪点: 300.2±30.1 °C
• 精确质量: 357.137634
• PSA: 66.84000
• LogP: 1.71
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.588
• 储存条件: 室温

安全

• 海关编码: 2934999090

合成路线

189028-93-1 ~% 1246853-49-5 189028-95-3

文献：Journal of Molecular Catalysis B: Enzymatic, , vol. 85-86, p. 99 - 104

1246853-48-4 ~% 1246853-49-5 189028-95-3

文献：Journal of Molecular Catalysis B: Enzymatic, , vol. 85-86, p. 99 - 104

189028-93-1 ~96% 189028-95-3

文献：SCHERING CORPORATION Patent: EP1137634 B1, 2005 ; Location in patent: Page/Page column 7 ;

108-05-4 1246853-48-4 ~76% 1246853-49-5 189028-95-3

文献：WO2010/113184 A1, ; Page/Page column 10 ;

67-63-0 189028-93-1 ~% 189028-95-3

文献：US2010/62499 A1, ;

上下游产品

上游产品  4
189028-93-1 108-05-4 1246853-48-4 67-63-0
下游产品  2
272778-12-8 163222-33-1

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%