495-19-2

• 常用中文名：1,2,5,6-四氢吡啶-3-羧酸甲酯
• 常用英文名：guvacoline
• CAS号：495-19-2
• 分子式：C₇H₁₂BrNO₂
• 分子量：222.08000
• 发布时间：2018-06-11 17:55:30
• 更新时间：2025-08-25 09:21:03

名称

• 中文名: 1,2,5,6-四氢吡啶-3-羧酸甲酯
• 英文名: guvacoline
• 英文别名: Norarecoline; methyl 1,2,3,6-tetrahydropyridine-5-carboxylate; methyl 1,2,5,6-tetrahydropyridine-3-carboxylate; Guvacoline; guvacine methyl ester; 5-methoxycarbonyl-1,2,3,6-tetrahydropyridine; methyl 1,2,5,6-tetrahydro-3-pyridinecarboxylate; 3-Methoxycarbonyl-1,2,5,6-tetrahydropyridine

物化性质

• 密度: 1.074g/cm3
• 沸点: 209.1ºC at 760mmHg
• 熔点: 144ºC
• 分子式: C₇H₁₂BrNO₂
• 分子量: 222.08000
• 闪点: 80.2ºC
• 精确质量: 221.00500
• PSA: 38.33000
• LogP: 1.36600
• 蒸汽压: 0.207mmHg at 25°C
• 折射率: 1.474

合成路线

63-75-2 ~95% 495-19-2

文献：Jakobsen, Palle; Lundbeck, Jane M; Kristiansen, Marit; Breinholt, Jens; Demuth, Helle; Pawlas, Jan; Torres Candela, Maria P; Andersen, Birgitte; Westergaard, Niels; Lundgren, Karsten; Asano, Naoki Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 3 p. 733 - 744

300-08-3 ~% 495-19-2

文献：Coldham, Iain; Crapnell, Katherine M; Fernandez, Joan-Carles; Moseley, Jonathan D; Rabot, Remi The Journal of organic chemistry, 2002 , vol. 67, # 17 p. 6181 - 6187

92600-27-6 ~84% 495-19-2

文献：Song, Song; Zhu, Shou-Fei; Pu, Liu-Yang; Zhou, Qi-Lin Angewandte Chemie - International Edition, 2013 , vol. 52, # 23 p. 6072 - 6075 Angew. Chem., 2013 , vol. 125, # 23 p. 6188 - 6191

121743-04-2 ~% 495-19-2 121743-23-5

文献：Clinch, K.; Marquez, C. J.; Parrott, M. J.; Ramage, R. Tetrahedron, 1989 , vol. 45, # 1 p. 239 - 258

67-56-1 ~% 495-19-2

文献：Hess Chemische Berichte, 1918 , vol. 51, p. 1014 Full Text Show Details Freudenberg Chemische Berichte, 1918 , vol. 51, p. 979,1675

上下游产品

上游产品  4
63-75-2 300-08-3 121743-04-2 67-56-1
下游产品  7
498-96-4 169105-89-9 86447-11-2 115103-54-3
163438-09-3 215725-59-0 38206-86-9