3254-93-1

• 常用中文名：去氧苯妥英
• 常用英文名：doxenitoin
• CAS号：3254-93-1
• 分子式：C₁₅H₁₄N₂O
• 分子量：238.28400
• 相关类别： 原料药 神经系统用药 抗癫痫及抗惊厥药
• 发布时间：2018-08-05 17:01:22
• 更新时间：2024-01-02 00:10:23

名称

• 中文名: 去氧苯妥英
• 英文名: 5,5-diphenylimidazolidin-4-one
• 英文别名: Doxenitoina [INN-Spanish]; Doxenitoine [INN-French]; Doxenitoinum [INN-Latin]; LG-1; 5,5-Diphenyl-imidazolidin-4-on; 5,5-Diphenyl-4-imidazolidinone; Glior; 5,5-diphenyl-imidazolidin-4-one; 5.5-Diphenyl-imidazolid-4-on; 5,5-diphenylpyrrolidinone; Doxenitoin; EINECS 221-851-6; SKF 2599

物化性质

• 密度: 1.167g/cm3
• 沸点: 454.7ºC at 760mmHg
• 熔点: 183° (Goodman); mp 185.5-186.5° (Biltz)
• 分子式: C₁₅H₁₄N₂O
• 分子量: 238.28400
• 闪点: 186.4ºC
• 精确质量: 238.11100
• PSA: 41.13000
• LogP: 2.26470
• 折射率: 1.596

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NJ0683000 CHEMICAL NAME : 4-Imidazolidinone, 5,5-diphenyl- CAS REGISTRY NUMBER : 3254-93-1 BEILSTEIN REFERENCE NO. : 0018626 LAST UPDATED : 199712 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C15-H14-N2-O MOLECULAR WEIGHT : 238.31 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 14,117,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 103 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 14,117,1959

安全

• 危险品运输编码: UN 3249
• 包装等级: III
• 危险类别: 6.1(b)
• 海关编码: 2933990090

合成路线

21083-47-6 ~92% 3254-93-1

文献：Khurana, Jitender M.; Agrawal, Arpita; Bansal, Geeti Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 5 p. 1007 - 1010

408529-54-4 ~% 3254-93-1

文献：Whalley et al. Journal of the American Chemical Society, 1955 , vol. 77, p. 745,748

21083-47-6 ~% 16459-51-1 3254-93-1

文献：Stanek; Sidlo Cesko-Slovenska Farmacie, 1953 , vol. 2, p. 117,119 Chem.Abstr., 1955 , p. 6123 Full Text Show Details Stanek; Sidlo Chemicke Listy, 1953 , vol. 47, p. 89 Chem.Abstr., 1954 , p. 3267 Full Text Show Details Terakawa Yakugaku Zasshi, 1955 , vol. 75, p. 320 Chem.Abstr., 1956 , p. 1693

71-41-0 21083-47-6 ~% 3254-93-1

文献：Biltz; Seydel Justus Liebigs Annalen der Chemie, 1912 , vol. 391, p. 218

上下游产品

上游产品  3
21083-47-6 408529-54-4 71-41-0
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%