1047-16-1

• 常用中文名：喹吖啶酮
• 常用英文名：Pigment Violet 19
• CAS号：1047-16-1
• 分子式：C₂₀H₁₂N₂O₂
• 分子量：312.32100
• 相关类别： 染料及颜料 颜料
• 发布时间：2018-05-20 08:00:00
• 更新时间：2024-01-05 20:01:42
• 【用途一】
  用于塑料、油漆、油墨、橡胶及合成纤维原液着色
  【用途二】
  用于塑料、油漆、油墨、合成橡胶的着色
  【用途三】
  主要用于塑料、涂料和油墨的着色。
  【用途四】
  主要用于塑料、涂料、树脂、涂料印花、油墨、橡胶和有机玻璃等的着色，也可用于合成纤维的原浆着色。

名称

• 中文名: 喹吖啶酮
• 英文名: Quinacridone
• 中文别名: C.I.颜料紫19; 颜料紫19
• 英文别名: 5,12-Dihydroquin[2,3-b]acridine-7,14-dione; EINECS 213-561-3; Pigment Violet 19; 5,12-dihydroquinolino[2,3-b]acridine-7,14-dione; MFCD00059956

物化性质

• 密度: 1.371 g/cm3
• 沸点: 568.5ºC at 760 mmHg
• 熔点: 390 °C
• 分子式: C₂₀H₁₂N₂O₂
• 分子量: 312.32100
• 闪点: 221.3ºC
• 精确质量: 312.09000
• PSA: 65.72000
• LogP: 3.67600
• 外观性状: 红色粉末
• 储存条件: 存放于惰性气体之中;避免空气
• 稳定性:

  色泽鲜艳。各项牢度性能优异，耐有机溶剂和耐热性高，与四氟乙烯混合、经430ºC高温挤压不变色，并在各种塑料中不迁移。耐晒性和耐气候性优良，即使高度稀释仍不降低其牢度。

• 分子结构:

  1、 摩尔折射率：91.21

  2、 摩尔体积（cm³/mol）：228.7

  3、 等张比容（90.2K）：645.3

  4、 表面张力（dyne/cm）：63.3

  5、 介电常数：无可用

  6、 偶极距（10^-24cm³）：无可用

  7、 极化率：36.16

• 计算化学:

  1.疏水参数计算参考值（XlogP）:4

  2.氢键供体数量:2

  3.氢键受体数量:4

  4.可旋转化学键数量:0

  5.互变异构体数量:3

  6.拓扑分子极性表面积58.2

  7.重原子数量:24

  8.表面电荷:0

  9.复杂度:500

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：艳紫色粉末。

  2. 密度（g/cm³,25℃）：1.48

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：390

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,8mm）：未确定

  7. 折射率：未确定

  8. 闪点（ºC）：未确定

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,25ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：不溶于水，乙醇中。

MSDS

Section I.Chemical Product and Company Identification Chemical Name Quinacridone (purified by sublimation) Portland OR SynonymQuino[2,3-b]acridine-7,14-dione, 5,12-dihydro- (CA INDEX NAME); 5,12-Dihydroquin[2,3-b]acridine- 7,14-dione; Pigment Violet 19; CI# 46500; CI# 73900 Chemical FormulaC20H12N2O2 CAS Number1047-16-1 Section II.Composition and Information on Ingredients Chemical NameCAS Number Percent (%)TLV/PELToxicology Data Quinacridone (purified by sublimation)Min. 99.0 (N) Not available.Rat LD50 (oral) >20 mL/kg 1047-16-1 Section III. Hazards Identification No specific information is available in our data base regarding the toxic effects of this material for humans. However, Acute Health Effects exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this compound. CARCINOGENIC EFFECTS : Not available. Chronic Health Effects MUTAGENIC EFFECTS : Not available. TERATOGENIC EFFECTS : Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Section IV.First Aid Measures Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention. Skin ContactIn case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. InhalationIf the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not improve. IngestionINDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Section V.Fire and Explosion Data Not available. FlammabilityMay be combustible at high temperature.Auto-Ignition Flash PointsNot available.Flammable LimitsNot available. Combustion ProductsThese products are toxic carbon oxides (CO, CO2), nitrogen oxides (NO, NO2). Fire Hazards Not available. Explosion HazardsRisks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in presence of static discharge: Not available. Fire Fighting MediaSMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet. and Instructions Consult with local fire authorities before attempting large scale fire-fighting operations. Continued on Next Page Quinacridone (purified by sublimation) Section VI.Accidental Release Measures Spill CleanupUse a shovel to put the material into a convenient waste disposal container. Finish cleaning the spill by rinsing any contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities for assistance on Instructions disposal. Section VII. Handling and Storage Handling and StorageKeep away from heat. Mechanical exhaust required. When not in use, tightly seal the container and store in a dry, cool place. Avoid excessive heat and light. Do not breathe dust. Information Always store away from incompatible compounds such as oxidizing agents. Section VIII. Exposure Controls/Personal Protection Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended Engineering Controls exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Splash goggles. Lab coat. Dust respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a Personal Protection specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent. Exposure LimitsNot available. Section IX. Physical and Chemical Properties Solid. (Yellowish-red crystal ~ powder.)Solubility Physical state @ 20°CNot available. Not available. Specific Gravity 312.32 Molecular WeightPartition CoefficientNot available. Boiling PointNot available.Vapor PressureNot applicable. 390°C (734°F)Not available. Melting PointVapor Density Not available.VolatilityNot available. Refractive Index Not available. Critical TemperatureNot available.Odor ViscosityNot available.TasteNot available. Section X.Stability and Reactivity Data Stability This material is stable if stored under proper conditions. (See Section VII for instructions) Conditions of InstabilityAvoid excessive heat and light. Incompatibilities Reactive with oxidizing agents. Section XI. Toxicological Information VA8533500 RTECS Number Routes of ExposureEye Contact. Ingestion. Inhalation. Rat LD50 (oral) >20 mL/kg Toxicity Data Chronic Toxic EffectsCARCINOGENIC EFFECTS : Not available. MUTAGENIC EFFECTS : Not available. TERATOGENIC EFFECTS : Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Acute Toxic EffectsNo specific information is available in our data base regarding the toxic effects of this material for humans. However, exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this compound. Section XII.Ecological Information Not available. Ecotoxicity Not available. Environmental Fate Continued on Next Page Quinacridone (purified by sublimation) Section XIII. Disposal Considerations Waste DisposalRecycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section XIV. Transport Information Not a DOT controlled material (United States). DOT Classification PIN NumberNot applicable. Proper Shipping NameNot applicable. Packing Group (PG)Not applicable. DOT Pictograms Section XV. Other Regulatory Information and Pictograms TSCA Chemical InventoryThis compound is ON the EPA Toxic Substances Control Act (TSCA) inventory list. (EPA) WHMIS ClassificationOn DSL. (Canada) EINECS Number (EEC) 213-879-2 EEC Risk StatementsNot available. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

毒理学数据: 1、急性毒性：大鼠口经LD50：>20mL/kg,出现精神萎靡，睡意大增，腹泻 CHEMICAL IDENTIFICATION RTECS NUMBER : VA8533500 CHEMICAL NAME : Quino(2,3-b)acridine-7,14-dione, 5,12-dihydro- CAS REGISTRY NUMBER : 1047-16-1 LAST UPDATED : 199710 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C20-H12-N2-O2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >20 mL/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533794 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >2 mL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533795

安全

• RTECS号: VA8533500
• 海关编码: 2933990090

合成路线

5862-38-4 ~99% 1047-16-1

文献：MCA TECHNOLOGIES GMBH Patent: WO2005/85364 A1, 2005 ; Location in patent: Page/Page column 17 ;

10109-95-2 ~90% 1047-16-1

文献：MCA TECHNOLOGIES GMBH Patent: WO2005/85364 A1, 2005 ; Location in patent: Page/Page column 13 ;

67906-32-5 10109-95-2 10291-28-8 ~% 1047-16-1 详细

文献：US2005/11403 A1, ; Page 13 ;

4898-56-0 ~% 1047-16-1

文献：US2844484 , ;

上下游产品

上游产品  5
5862-38-4 10109-95-2 67906-32-5 10291-28-8
4898-56-0
下游产品  3
1503-48-6 19205-19-7 99762-80-8

制备

合成方法同喹吖啶酮红，由于晶型不同，在氧化步骤工艺不同，β型喹吖啶酮的氧化方法如下。
加入工业乙醇108kg，水45kg，工业固碱48kg，搅拌，再加入6，13-二氢基喹吖啶酮精制品滤饼10kg，搅拌30min，加入间硝基苯磺酸钠并升温回流4h，冷却至室温后，放入冷水250kg，自然数释，搅拌半小时，压滤，回收溶剂，滤饼于70℃下烘干，得量9.5kg。

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%