144702-26-1

• 常用中文名：4'-[[1,4'-二甲基-2'-丙基(2,6'-联-1H-苯并咪唑)-1'-甲基]-[1,1'-联苯基]-2-羧酸叔丁酯
• 常用英文名：4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester
• CAS号：144702-26-1
• 分子式：C₃₇H₃₈N₄O₂
• 分子量：570.72300
• 发布时间：2018-12-01 16:03:42
• 更新时间：2025-08-21 15:52:41

名称

• 中文名: 4'-[[1,4'-二甲基-2'-丙基(2,6'-联-1H-苯并咪唑)-1'-甲基]-[1,1'-联苯基]-2-羧酸叔丁酯
• 英文名: Telmisartan tert-Butyl Ester
• 中文别名: 替米沙坦杂质C; 替米沙坦杂质B; 沙坦类中间体
• 英文别名: tert-butyl 2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoate; 4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester; Telmisartan Impurity 3

物化性质

• 密度: 1.16
• 沸点: 780.446ºC at 760 mmHg
• 分子式: C₃₇H₃₈N₄O₂
• 分子量: 570.72300
• 闪点: 425.798ºC
• 精确质量: 570.29900
• PSA: 61.94000
• LogP: 8.52150
• 外观性状: 粉末
• 储存条件: 室温

合成路线

1190092-31-9 612-28-2 ~62% 144702-26-1

文献：ZAKLADY FARMACEUTYCZNE POLPHARMA SA Patent: WO2009/123483 A1, 2009 ; Location in patent: Page/Page column 18-19 ;

114772-40-6 152628-02-9 ~72% 144702-26-1

文献：Kumar, A. Sanjeev; Ghosh, Samir; Mehta Journal of Chemical Research, 2010 , # 2 p. 95 - 97

18595-14-7 ~% 144702-26-1

文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

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文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

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文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

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文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

675882-71-0 ~% 144702-26-1

文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

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文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

152628-03-0 ~% 144702-26-1

文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051