68252-72-2

• 常用中文名：N-[4-(AMINOSULFONYL)-2-CHLOROPHENYL!ACETAMIDE+
• 常用英文名：N-[4-(AMINOSULFONYL)-2-CHLOROPHENYL!ACETAMIDE+
• CAS号：68252-72-2
• 分子式：C₈H₉ClN₂O₃S
• 分子量：248.68700
• 发布时间：2017-04-11 23:10:28
• 更新时间：2023-01-17 17:50:49

名称

• 英文名: N-(2-Chloro-4-sulfamoylphenyl)acetamide
• 英文别名: Acetamide,N-(4-(aminosulfonyl)-2-chlorophenyl); N-(4-(Aminosulfonyl)-2-chlorophenyl)acetamide; 4-acetamido-3-chlorobenzenesulfonamide; PB 310

物化性质

• 密度: 1.521g/cm3
• 分子式: C₈H₉ClN₂O₃S
• 分子量: 248.68700
• 精确质量: 248.00200
• PSA: 101.13000
• LogP: 3.37640
• 折射率: 1.615

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AB4415000 CHEMICAL NAME : Acetamide, N-(4-(aminosulfonyl)-2-chlorophenyl)- CAS REGISTRY NUMBER : 68252-72-2 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H9-Cl-N2-O3-S MOLECULAR WEIGHT : 248.70 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,1331,1978

合成路线

16761-18-5 ~% 68252-72-2

文献：Ilies, Marc A.; Vullo, Daniela; Pastorek, Jaromir; Scozzafava, Andrea; Ilies, Monica; Caproiu, Miron T.; Pastorekova, Silvia; Supuran, Claudiu T. Journal of Medicinal Chemistry, 2003 , vol. 46, # 11 p. 2187 - 2196

533-17-5 ~% 68252-72-2

文献：Ilies, Marc A.; Vullo, Daniela; Pastorek, Jaromir; Scozzafava, Andrea; Ilies, Monica; Caproiu, Miron T.; Pastorekova, Silvia; Supuran, Claudiu T. Journal of Medicinal Chemistry, 2003 , vol. 46, # 11 p. 2187 - 2196

95-51-2 ~% 68252-72-2

文献：Ilies, Marc A.; Vullo, Daniela; Pastorek, Jaromir; Scozzafava, Andrea; Ilies, Monica; Caproiu, Miron T.; Pastorekova, Silvia; Supuran, Claudiu T. Journal of Medicinal Chemistry, 2003 , vol. 46, # 11 p. 2187 - 2196