189268-42-6

• 常用中文名：2-甲基-4-(1H-吡唑-1-基)-8-羟基喹啉
• 常用英文名：8-HYDROXY-2-METHYL-4-(1H-PYRAZOL-1-YL)QUINOLINE
• CAS号：189268-42-6
• 分子式：C₁₃H₁₁N₃O
• 分子量：225.24600
• 发布时间：2018-12-17 20:21:53
• 更新时间：2024-01-06 17:48:54

名称

• 中文名: 2-甲基-4-(1H-吡唑-1-基)-8-羟基喹啉
• 英文名: 2-methyl-4-pyrazol-1-ylquinolin-8-ol
• 英文别名: 8-Hydroxy-2-methyl-4-(pyrazol-1-yl)quinoline; 8-hydroxy-2-methyl-4-(1H-pyrazol-1-yl)quinoline; 2-methyl-4-pyrazol-1-yl-quinolin-8-ol; 2-methyl-4-(1H-pyrazol-1-yl)-8-quinolinol; 8-Quinolinol,2-methyl-4-(1H-pyrazol-1-yl)

物化性质

• 密度: 1.3g/cm3
• 沸点: 438ºC at 760mmHg
• 分子式: C₁₃H₁₁N₃O
• 分子量: 225.24600
• 闪点: 218.7ºC
• 精确质量: 225.09000
• PSA: 50.94000
• LogP: 2.43450
• 蒸汽压: 2.78E-08mmHg at 25°C
• 折射率: 1.682

合成路线

288-13-1 28507-46-2 ~81% 189268-42-6

文献：Sawada, Yuki; Kayakiri, Hiroshi; Abe, Yoshito; Imai, Keisuke; Mizutani, Tsuyoshi; Inamura, Noriaki; Asano, Masayuki; Aramori, Ichiro; Hatori, Chie; Katayama, Akira; Oku, Teruo; Tanaka, Hirokazu Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1617 - 1630

28507-46-2 ~% 189268-42-6

文献：Fujisawa Pharmaceutical Co., Ltd. Patent: US6083959 A1, 2000 ;

28507-46-2 ~% 54666-28-3 189268-42-6

文献：Fujisawa Pharmaceutical Co., Ltd. Patent: US6008229 A1, 1999 ;

15644-89-0 ~% 189268-42-6

文献：Sawada, Yuki; Kayakiri, Hiroshi; Abe, Yoshito; Imai, Keisuke; Mizutani, Tsuyoshi; Inamura, Noriaki; Asano, Masayuki; Aramori, Ichiro; Hatori, Chie; Katayama, Akira; Oku, Teruo; Tanaka, Hirokazu Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1617 - 1630

64951-58-2 ~% 189268-42-6

文献：Sawada, Yuki; Kayakiri, Hiroshi; Abe, Yoshito; Imai, Keisuke; Mizutani, Tsuyoshi; Inamura, Noriaki; Asano, Masayuki; Aramori, Ichiro; Hatori, Chie; Katayama, Akira; Oku, Teruo; Tanaka, Hirokazu Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1617 - 1630

33267-45-7 ~% 189268-42-6

文献：Sawada, Yuki; Kayakiri, Hiroshi; Abe, Yoshito; Imai, Keisuke; Mizutani, Tsuyoshi; Inamura, Noriaki; Asano, Masayuki; Aramori, Ichiro; Hatori, Chie; Katayama, Akira; Oku, Teruo; Tanaka, Hirokazu Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1617 - 1630

90-04-0 ~% 189268-42-6

文献：Sawada, Yuki; Kayakiri, Hiroshi; Abe, Yoshito; Imai, Keisuke; Mizutani, Tsuyoshi; Inamura, Noriaki; Asano, Masayuki; Aramori, Ichiro; Hatori, Chie; Katayama, Akira; Oku, Teruo; Tanaka, Hirokazu Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1617 - 1630