67227-04-7

• 常用中文名：2-[2-(2,6-dimethylanilino)ethyl]guanidine
• 常用英文名：2-[2-(2,6-dimethylanilino)ethyl]guanidine
• CAS号：67227-04-7
• 分子式：C₁₁H₁₈N₄
• 分子量：206.28700
• 发布时间：2016-03-15 07:03:11
• 更新时间：2024-01-03 22:08:43

名称

• 英文名: 2-[2-(2,6-dimethylanilino)ethyl]guanidine

物化性质

• 密度: 1.13g/cm3
• 沸点: 409.6ºC at 760 mmHg
• 分子式: C₁₁H₁₈N₄
• 分子量: 206.28700
• 闪点: 201.5ºC
• 精确质量: 206.15300
• PSA: 73.93000
• LogP: 2.46230
• 折射率: 1.574

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MF7355000 CHEMICAL NAME : Guanidine, (2-(2,6-xylidino)ethyl)- CAS REGISTRY NUMBER : 67227-04-7 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H18-N4 MOLECULAR WEIGHT : 206.33 WISWESSER LINE NOTATION : MUYZM2MR B1 F1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 750 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,705,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,705,1963

合成路线

75889-19-9 ~% 67227-04-7

文献：Barron,D.I. et al. J. Med. Chem., 1963 , vol. 6, p. 705 - 711

71319-67-0 14527-26-5 ~% 67227-04-7

文献：Barron,D.I. et al. J. Med. Chem., 1963 , vol. 6, p. 705 - 711