3567-38-2

• 常用中文名：卡非氨酯
• 常用英文名：Phenylethynylcarbinol carbamate
• CAS号：3567-38-2
• 分子式：C₁₀H₉NO₂
• 分子量：175.18400
• 相关类别： 研究领域 神经疾病
• 发布时间：2018-06-18 16:07:24
• 更新时间：2025-08-28 23:15:32
• 苯乙炔基甲醇氨基甲酸酯是一种催眠剂[1]。

名称

• 中文名: 卡非氨酯
• 英文名: 1-phenylprop-2-ynyl carbamate
• 英文别名: Phenylethynylcarbinol carbamate; Carfimat; 1-Phenyl-2-propynyl carbamate; Nirvotin; Carfimate

物化性质

• 密度: 1.192g/cm3
• 沸点: 320.2ºC at 760mmHg
• 分子式: C₁₀H₉NO₂
• 分子量: 175.18400
• 闪点: 165.2ºC
• 精确质量: 175.06300
• PSA: 53.31000
• LogP: 1.97000
• 折射率: 1.569

生物活性

• 描述: 苯乙炔基甲醇氨基甲酸酯是一种催眠剂[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. GHISONI T. A proposito di un nuovo ipnotico, carbammato di fenil-etinil-carbinolo [A new hypnotic drug, phenylethynylcarbinol carbamate]. Gazz Med Ital. 1956;115(8):242-247.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DO5950000 CHEMICAL NAME : Benzyl alcohol, alpha-ethynyl-, carbamate CAS REGISTRY NUMBER : 3567-38-2 BEILSTEIN REFERENCE NO. : 3200625 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C10-H9-N-O2 MOLECULAR WEIGHT : 175.20 WISWESSER LINE NOTATION : ZVOYR&1UU1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 99,245,1954 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 99,245,1954 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 6,136,1956

安全

• 海关编码: 2924299090

合成路线

590-28-3 4187-87-5 ~% 3567-38-2

文献：Hudlicky,M. Collection of Czechoslovak Chemical Communications, 1960 , vol. 25, p. 1199 - 1209

463-72-9 4187-87-5 ~% 3567-38-2

文献：Logemann et al. Farmaco, Edizione Scientifica, 1953 , vol. 8, p. 406,409

4187-87-5 1885-14-9 ~% 3567-38-2

文献：Dillard,R.D. et al. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 40 - 44

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%