475060-21-0

• 常用中文名：N-(5-氟-4-甲基吡啶-2-基)乙酰胺
• 常用英文名：N-(5-Fluoro-4-methyl-2-pyridinyl)acetamide
• CAS号：475060-21-0
• 分子式：C₈H₉FN₂O
• 分子量：168.168
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 甲基吡啶
• 发布时间：2019-01-09 18:02:14
• 更新时间：2025-08-25 20:08:54

名称

• 中文名: N-(5-氟-4-甲基吡啶-2-基)乙酰胺
• 英文名: N-(5-fluoro-4-methylpyridin-2-yl)acetamide
• 中文别名: 2-乙酰胺-5-氟-4-甲基吡啶
• 英文别名: N-(5-Fluoro-4-Methyl-2-Pyridinyl)-Acetamide; N-(5-Fluoro-4-methyl-2-pyridinyl)acetamide; N-(5-Fluoro-4-methylpyridin-2-yl)acetamide; N1-(5-fluoro-4-methyl-pyridin-2-yl)acetamide; N1-(5-fluoro-4-methyl-2-pyridyl)acetamide; 2-Acetamido-5-fluoro-4-picoline; Acetamide, N-(5-fluoro-4-methyl-2-pyridinyl)-; 2-Acetamido-5-fluoro-4-methylpyridine

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 321.4±42.0 °C at 760 mmHg
• 分子式: C₈H₉FN₂O
• 分子量: 168.168
• 闪点: 148.2±27.9 °C
• 精确质量: 168.069885
• PSA: 41.99000
• LogP: 1.30
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.551

合成路线

21901-40-6 ~% 475060-21-0

文献：Nakayama, Kiyoshi; Kuru, Noriko; Ohtsuka, Masami; Yokomizo, Yoshihiro; Sakamoto, Atsunobu; Kawato, Haruko; Yoshida, Ken-Ichi; Ohta, Toshiharu; Hoshino, Kazuki; Akimoto, Katsuya; Itoh, Junko; Ishida, Hiroko; Cho, Aesop; Palme, Monica H.; Zhang, Jason Z.; Lee, Ving J.; Watkins, William J. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 10 p. 2493 - 2497

90765-02-9 ~% 475060-21-0

文献：Nakayama, Kiyoshi; Kuru, Noriko; Ohtsuka, Masami; Yokomizo, Yoshihiro; Sakamoto, Atsunobu; Kawato, Haruko; Yoshida, Ken-Ichi; Ohta, Toshiharu; Hoshino, Kazuki; Akimoto, Katsuya; Itoh, Junko; Ishida, Hiroko; Cho, Aesop; Palme, Monica H.; Zhang, Jason Z.; Lee, Ving J.; Watkins, William J. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 10 p. 2493 - 2497

475060-18-5 ~% 475060-21-0

文献：Nakayama, Kiyoshi; Kuru, Noriko; Ohtsuka, Masami; Yokomizo, Yoshihiro; Sakamoto, Atsunobu; Kawato, Haruko; Yoshida, Ken-Ichi; Ohta, Toshiharu; Hoshino, Kazuki; Akimoto, Katsuya; Itoh, Junko; Ishida, Hiroko; Cho, Aesop; Palme, Monica H.; Zhang, Jason Z.; Lee, Ving J.; Watkins, William J. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 10 p. 2493 - 2497

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