61881-50-3

• 常用中文名：diethyl 2-[(4-aminophenyl)methyl]propanedioate
• 常用英文名：diethyl 2-[(4-aminophenyl)methyl]propanedioate
• CAS号：61881-50-3
• 分子式：C₁₄H₁₉NO₄
• 分子量：265.30500
• 发布时间：2017-06-24 05:56:26
• 更新时间：2024-01-10 19:16:56

名称

• 英文名: diethyl 2-[(4-aminophenyl)methyl]propanedioate
• 英文别名: diethyl 2-(4-aminophenyl)-2-methylmalonate; Diethyl-(4-aminophenyl)-methylmalonat; Propanedioic acid,(4-aminophenyl)methyl-,diethyl ester; amino-4-phenyl methyl malonate d'ethyle; 2-(4-Aminophenyl)-2-methylmalonsaeure-diethylester

物化性质

• 分子式: C₁₄H₁₉NO₄
• 分子量: 265.30500
• 精确质量: 265.13100
• PSA: 78.62000
• LogP: 2.13490

合成路线

61881-49-0 ~98% 61881-50-3

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: US2012/46304 A1, 2012 ; Location in patent: Page/Page column 177 ;

350-46-9 ~% 61881-50-3

文献：Peretto, Ilaria; Radaelli, Stefano; Parini, Carlo; Zandi, Michele; Raveglia, Luca F.; Dondio, Giulio; Fontanella, Laura; Misiano, Paola; Bigogno, Chiara; Rizzi, Andrea; Riccardi, Benedetta; Biscaioli, Marcello; Marchetti, Silvia; Puccini, Paola; Catinella, Silvia; Rondelli, Ivano; Cenacchi, Valentina; Bolzoni, Pier Tonino; Caruso, Paola; Villetti, Gino; Facchinetti, Fabrizio; Del Giudice, Elda; Moretto, Nadia; Imbimbo, Bruno P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5705 - 5720

609-08-5 ~% 61881-50-3

文献：Peretto, Ilaria; Radaelli, Stefano; Parini, Carlo; Zandi, Michele; Raveglia, Luca F.; Dondio, Giulio; Fontanella, Laura; Misiano, Paola; Bigogno, Chiara; Rizzi, Andrea; Riccardi, Benedetta; Biscaioli, Marcello; Marchetti, Silvia; Puccini, Paola; Catinella, Silvia; Rondelli, Ivano; Cenacchi, Valentina; Bolzoni, Pier Tonino; Caruso, Paola; Villetti, Gino; Facchinetti, Fabrizio; Del Giudice, Elda; Moretto, Nadia; Imbimbo, Bruno P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5705 - 5720

100-00-5 ~% 61881-50-3

文献：Naito; Goto; Akahoshi; Ono; Yoshitomi; Okano; Sugiyama; Abe; Hanada; Hirata; Watanabe; Fukaya; Yokoyama; Fujita Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 9 p. 2323 - 2332

18424-77-6 350-46-9 ~% 61881-50-3

文献：Dunwell,D.W.; Evans,D. Journal of Medicinal Chemistry, 1977 , vol. 20, p. 797 - 801