380499-07-0

• 常用中文名：(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine
• 常用英文名：(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine
• CAS号：380499-07-0
• 分子式：C₂₀H₁₆F₇NO₂
• 分子量：435.33500
• 发布时间：2016-02-26 03:54:28
• 更新时间：2025-08-26 14:48:02

名称

• 英文名: (6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine

物化性质

• 分子式: C₂₀H₁₆F₇NO₂
• 分子量: 435.33500
• 精确质量: 435.10700
• PSA: 30.82000
• LogP: 5.22210

合成路线

380499-06-9 ~90% 380499-07-0

文献：Sandoz AG Patent: WO2009/106486 A1, 2009 ; Location in patent: Page/Page column 15; 4 ;

368-63-8 ~% 380499-07-0

文献：Zhao, Matthew M.; McNamara, James M.; Ho, Guo-Jie; Emerson, Khateeta M.; Song, Zhiguo J.; Tschaen, David M.; Brands, Karel M. J.; Dolling, Ulf-H; Grabowski, Edward J. J.; Reider, Paul J.; Cottrell, Ian F.; Ashwood, Michael S.; Bishop, Brian C. Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6743 - 6747

472968-68-6 ~% 380499-07-0

文献：Zhao, Matthew M.; McNamara, James M.; Ho, Guo-Jie; Emerson, Khateeta M.; Song, Zhiguo J.; Tschaen, David M.; Brands, Karel M. J.; Dolling, Ulf-H; Grabowski, Edward J. J.; Reider, Paul J.; Cottrell, Ian F.; Ashwood, Michael S.; Bishop, Brian C. Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6743 - 6747

472968-69-7 ~% 380499-07-0

文献：Zhao, Matthew M.; McNamara, James M.; Ho, Guo-Jie; Emerson, Khateeta M.; Song, Zhiguo J.; Tschaen, David M.; Brands, Karel M. J.; Dolling, Ulf-H; Grabowski, Edward J. J.; Reider, Paul J.; Cottrell, Ian F.; Ashwood, Michael S.; Bishop, Brian C. Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6743 - 6747

472968-70-0 ~% 380499-07-0

文献：Zhao, Matthew M.; McNamara, James M.; Ho, Guo-Jie; Emerson, Khateeta M.; Song, Zhiguo J.; Tschaen, David M.; Brands, Karel M. J.; Dolling, Ulf-H; Grabowski, Edward J. J.; Reider, Paul J.; Cottrell, Ian F.; Ashwood, Michael S.; Bishop, Brian C. Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6743 - 6747

上下游产品

上游产品  2
380499-06-9 368-63-8
下游产品  3
171338-27-5 380499-06-9 170729-80-3