955016-62-3

• 常用中文名：2-氰基-1,4-哌嗪二羧酸 4-叔丁酯 1-苯甲酯
• 常用英文名：1-O-benzyl 4-O-tert-butyl 2-cyanopiperazine-1,4-dicarboxylate
• CAS号：955016-62-3
• 分子式：C₁₈H₂₃N₃O₄
• 分子量：345.39300
• 发布时间：2017-06-04 20:33:39
• 更新时间：2025-11-29 08:52:56

名称

• 中文名: 2-氰基-1,4-哌嗪二羧酸 4-叔丁酯 1-苯甲酯
• 英文名: 1-O-benzyl 4-O-tert-butyl 2-cyanopiperazine-1,4-dicarboxylate
• 中文别名: 1-CBZ-4-BOC-2-氰基哌嗪; 1-苄基4-(叔丁基)2-氰基哌嗪-1,4-二羧酸酯; 4-BOC-1-CBZ-哌嗪-2-甲腈
• 英文别名: 4-Boc-1-Cbz-piperazine-2-carbonitrile; 1-benzyl 4-tert-butyl 3-cyanopiperazine-1,4-dicarboxylate; 4-benzyl 1-tert-butyl 3-cyanopiperazin-1,4-dicboxylate; 1-O-benzyl 4-O-tert-butyl 2-cyanopiperazine-1,4-dicboxylate; 1-benzyl 4-tert-butyl 2-cyanopiperazine-1,4-dicboxylate; 2-Cyano-1,4-piperazinedicboxylic acid 4-(tert-butyl) 1-(phenylmethyl) ester; 1,4-Piperazinedicboxylic acid, 2-cyano-, 4-(1,1-dimethylethyl) 1-(phenylmethyl) ester; 1-benzyl 4-tert-butyl 2-cyanopiperazine-1,4-dicarboxylate; 4-benzyl 1-tert-butyl 3-cyanopiperidine-1,4-dicboxylate; 4-Boc-1-Cbz-2-cyanopiperazine

物化性质

• 分子式: C₁₈H₂₃N₃O₄
• 分子量: 345.39300
• 精确质量: 345.16900
• PSA: 82.87000
• LogP: 2.64388

合成路线

955016-61-2 ~99% 955016-62-3

文献：Gardelli, Cristina; Nizi, Emanuela; Muraglia, Ester; Crescenzi, Benedetta; Ferrara, Marco; Orvieto, Federica; Pace, Paola; Pescatore, Giovanna; Poma, Marco; Ferreira, Maria Del Rosario Rico; Scarpelli, Rita; Homnick, Carl F.; Ikemoto, Norihiro; Alfieri, Anna; Verdirame, Maria; Bonelli, Fabio; Paz, Odalys Gonzalez; Taliani, Marina; Monteagudo, Edith; Pesci, Silvia; Laufer, Ralph; Felock, Peter; Stillmock, Kara A.; Hazuda, Daria; Rowley, Michael; Summa, Vincenzo Journal of Medicinal Chemistry, 2007 , vol. 50, # 20 p. 4953 - 4975

126937-41-5 ~% 955016-62-3

文献：Pace, Paola; Di Francesco, M. Emilia; Gardelli, Cristina; Harper, Steven; Muraglia, Ester; Nizi, Emanuela; Orvieto, Federica; Petrocchi, Alessia; Poma, Marco; Rowley, Michael; Scarpelli, Rita; Laufer, Ralph; Paz, Odalys Gonzalez; Monteagudo, Edith; Bonelli, Fabio; Hazuda, Daria; Stillmock, Kara A.; Summa, Vincenzo Journal of Medicinal Chemistry, 2007 , vol. 50, # 9 p. 2225 - 2239