857265-74-8

• 常用中文名：5-乙炔嘧啶-2-胺
• 常用英文名：2-Pyrimidinamine, 5-ethynyl- (9CI)
• CAS号：857265-74-8
• 分子式：C₆H₅N₃
• 分子量：119.12400
• 发布时间：2018-05-31 08:00:00
• 更新时间：2025-09-25 20:59:42

名称

• 中文名: 5-乙炔嘧啶-2-胺
• 英文名: 5-ethynylpyrimidin-2-amine
• 英文别名: 2-PYRIMIDINAMINE,5-ETHYNYL; 5-ETHYNYL-2-PYRIMIDINAMINE; 2-amino-5-ethynylpyrimidine

物化性质

• 分子式: C₆H₅N₃
• 分子量: 119.12400
• 精确质量: 119.04800
• PSA: 52.53000

合成路线

857265-75-9 ~99% 857265-74-8

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2005/60970 A1, 2005 ; Location in patent: Page/Page column 118 ; WO 2005/060970 A1

1445-39-2 1066-54-2 ~82% 857265-74-8

文献：Cee, Victor J.; Albrecht, Brian K.; Geuns-Meyer, Stephanie; Hughes, Paul; Bellon, Steve; Bready, James; Caenepeel, Sean; Chaffee, Stuart C.; Coxon, Angela; Emery, Maurice; Fretland, Jenne; Gallant, Paul; Gu, Yan; Hodous, Brian L.; Hoffman, Doug; Johnson, Rebecca E.; Kendall, Richard; Kim, Joseph L.; Long, Alexander M.; McGowan, David; Morrison, Michael; Olivieri, Philip R.; Patel, Vinod F.; Polverino, Anthony; Powers, David; Rose, Paul; Wang, Ling; Zhao, Huilin Journal of Medicinal Chemistry, 2007 , vol. 50, # 4 p. 627 - 640

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