137795-35-8

• 常用中文名：螺谷胺
• 常用英文名：(4R)-5-(8-azaspiro[4.5]decan-8-yl)-4-[(3,5-dichlorobenzoyl)amino]-5-oxopentanoic acid
• CAS号：137795-35-8
• 分子式：C₂₁H₂₆Cl₂N₂O₄
• 分子量：441.34800
• 发布时间：2018-09-22 12:18:20
• 更新时间：2025-09-01 17:49:08

名称

• 中文名: 螺谷胺
• 英文名: (4R)-5-(8-azaspiro[4.5]decan-8-yl)-4-[(3,5-dichlorobenzoyl)amino]-5-oxopentanoic acid
• 英文别名: Spiroglumide; Radaxafine HCl; UNII-EZS5V8UN4Y

物化性质

• 密度: 1.36g/cm3
• 沸点: 654.8ºC at 760 mmHg
• 分子式: C₂₁H₂₆Cl₂N₂O₄
• 分子量: 441.34800
• 闪点: 349.8ºC
• 精确质量: 440.12700
• PSA: 90.20000
• LogP: 4.65210
• 蒸汽压: 4.89E-18mmHg at 25°C
• 折射率: 1.605

合成路线

176-64-7 ~% 137795-35-8

文献：Makovec, Francesco; Peris, Walter; Revel, Laura; Giovanetti, Roberto; Mennuni, Laura; Rovati, Lucio C. Journal of Medicinal Chemistry, 1992 , vol. 35, # 1 p. 28 - 38

59486-73-6 ~% 137795-35-8

文献：Makovec, Francesco; Peris, Walter; Revel, Laura; Giovanetti, Roberto; Mennuni, Laura; Rovati, Lucio C. Journal of Medicinal Chemistry, 1992 , vol. 35, # 1 p. 28 - 38

137822-90-3 ~% 137795-35-8

文献：Makovec, Francesco; Peris, Walter; Revel, Laura; Giovanetti, Roberto; Mennuni, Laura; Rovati, Lucio C. Journal of Medicinal Chemistry, 1992 , vol. 35, # 1 p. 28 - 38

2905-62-6 137795-97-2 ~% 137795-35-8

文献：Makovec, Francesco; Peris, Walter; Revel, Laura; Giovanetti, Roberto; Mennuni, Laura; Rovati, Lucio C. Journal of Medicinal Chemistry, 1992 , vol. 35, # 1 p. 28 - 38