145508-78-7

• 常用中文名：艾考哌齐
• 常用英文名：3-[2-(1-benzylpiperidin-4-yl)ethyl]-2,5-dihydropyrrolo[3,2-f][1,2]benzoxazol-6-one
• CAS号：145508-78-7
• 分子式：C₂₃H₂₅N₃O₂
• 分子量：375.46400
• 发布时间：2018-07-05 10:35:30
• 更新时间：2025-08-25 16:51:28

名称

• 中文名: 艾考哌齐
• 英文名: 3-[2-(1-benzylpiperidin-4-yl)ethyl]-2,5-dihydropyrrolo[3,2-f][1,2]benzoxazol-6-one
• 英文别名: 5,7-dihydro-3-[2-[1-(phenyl-methyl)-4-piperidinyl]ethyl]-6H-pyrrolo[3,2-f]-1,2-benzisoxazol-6-one; UNII-ERZ60E6B7C; 3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-5,7-dihydro-1-oxa-2,7-diaza-s-indacene-6-one; Icopezil maleate; Icopezil; 5,7-Dihydro-3-[2-[1-benzylpiperidin-4yl]ethyl]-6H-pyrrolo[4,5-f]-1.2-benzisoxazol-6-one; 5,7-dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-6H-pyrrolo[4,5-f]-1,2-benzisoxazol-6-one; 6,7-dihydro-3-{2-[1-(phenylmethyl)-4-piperidyl]ethyl}-5H-pyrrolo[3,2-f][1,2]benzoxazol-6-one; Icopezil [INN]

物化性质

• 密度: 1.227g/cm3
• 沸点: 581.4ºC at 760mmHg
• 分子式: C₂₃H₂₅N₃O₂
• 分子量: 375.46400
• 闪点: 305.4ºC
• 精确质量: 375.19500
• PSA: 61.86000
• LogP: 4.19020
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.63

合成路线

145509-11-1 ~% 145508-78-7

文献：Villalobos; Butler; Chapin; Chen; DeMattos; Ives; Jones; Liston; Nagel; Nason; Nielsen; Ramirez; Shalaby; White Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2802 - 2808

166756-71-4 ~% 145508-78-7

文献：Villalobos; Butler; Chapin; Chen; DeMattos; Ives; Jones; Liston; Nagel; Nason; Nielsen; Ramirez; Shalaby; White Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2802 - 2808

145509-12-2 ~% 145508-78-7

文献：Villalobos; Butler; Chapin; Chen; DeMattos; Ives; Jones; Liston; Nagel; Nason; Nielsen; Ramirez; Shalaby; White Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2802 - 2808

145508-94-7 ~% 145508-78-7

文献：Villalobos; Butler; Chapin; Chen; DeMattos; Ives; Jones; Liston; Nagel; Nason; Nielsen; Ramirez; Shalaby; White Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2802 - 2808