75787-33-6

• 常用中文名：2,4(1H,3H)-Quinazolinedione, 7-chloro-3-(dimethylamino)-
• 常用英文名：2,4(1H,3H)-Quinazolinedione, 7-chloro-3-(dimethylamino)-
• CAS号：75787-33-6
• 分子式：C₁₀H₁₀ClN₃O₂
• 分子量：239.65800
• 发布时间：2016-11-28 22:04:20
• 更新时间：2024-01-09 20:36:36

名称

• 英文名: 7-chloro-3-(dimethylamino)-1H-quinazoline-2,4-dione
• 英文别名: chloro-7 dimethylamino-3 1H,3H quinazolinedione-2,4; 7-chloro-3-dimethylamino-1H-quinazoline-2,4-dione

物化性质

• 密度: 1.47g/cm3
• 分子式: C₁₀H₁₀ClN₃O₂
• 分子量: 239.65800
• 精确质量: 239.04600
• PSA: 58.36000
• LogP: 0.95310
• 折射率: 1.654

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VA1395300 CHEMICAL NAME : 2,4(1H,3H)-Quinazolinedione, 7-chloro-3-(dimethylamino)- CAS REGISTRY NUMBER : 75787-33-6 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C10-H10-Cl-N3-O2 MOLECULAR WEIGHT : 239.68 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 18,241,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 425 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 18,241,1983

合成路线

40928-13-0 ~% 75787-33-6

文献：Baronnet; Callendret; Blanchard; et al. European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 241 - 247

89-77-0 ~% 75787-33-6

文献：Baronnet; Callendret; Blanchard; et al. European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 241 - 247

75-44-5 75787-31-4 ~% 75787-33-6

文献：Baronnet; Callendret; Blanchard; et al. European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 241 - 247