603965-77-1

• 常用中文名：2-(哌嗪-1-基)嘧啶-5-羧酸乙酯
• 常用英文名：ETHYL 2-(PIPERAZIN-1-YL)PYRIMIDINE-5-CARBOXYLATE
• CAS号：603965-77-1
• 分子式：C₁₁H₁₆N₄O₂
• 分子量：236.27000
• 发布时间：2019-01-02 12:05:44
• 更新时间：2024-01-06 11:40:20

名称

• 中文名: 2-(哌嗪-1-基)嘧啶-5-羧酸乙酯
• 英文名: ethyl 2-piperazin-1-ylpyrimidine-5-carboxylate
• 英文别名: MFCD09910278

物化性质

• 密度: 1.189g/cm3
• 沸点: 407.2ºC at 760 mmHg
• 分子式: C₁₁H₁₆N₄O₂
• 分子量: 236.27000
• 闪点: 200.1ºC
• 精确质量: 236.12700
• PSA: 67.35000
• LogP: 0.45670
• 折射率: 1.54
• 储存条件: 2-8°C， 避光

安全

• 海关编码: 2933990090

合成路线

110-85-0 89793-12-4 ~86% 603965-77-1

文献：Curis, Inc.; Bao, Rudi; Lai, Chengjung; Qian, Changgeng Patent: US2013/102595 A1, 2013 ; Location in patent: Paragraph 0217 ;

253315-69-4 ~% 603965-77-1

文献：Zhang, Zaihui; Sun, Shaoyi; Kodumuru, Vishnumurthy; Hou, Duanjie; Liu, Shifeng; Chakka, Nagasree; Sviridov, Serguei; Chowdhury, Sultan; McLaren, David G.; Ratkay, Leslie G.; Khakh, Kuldip; Cheng, Xing; Gschwend, Heinz W.; Kamboj, Rajender; Fu, Jianmin; Winther, Michael D. Journal of Medicinal Chemistry, 2013 , vol. 56, # 2 p. 568 - 583

763-69-9 ~% 603965-77-1

文献：CURIS, INC.; BAO, Rudi; LAI, Chengjung; QIAN, Changgeng Patent: WO2011/130628 A1, 2011 ; WO 2011/130628 A1

33458-27-4 ~% 603965-77-1

文献：CURIS, INC.; BAO, Rudi; LAI, Chengjung; QIAN, Changgeng Patent: WO2011/130628 A1, 2011 ; WO 2011/130628 A1

95928-49-7 ~% 603965-77-1

文献：CURIS, INC.; BAO, Rudi; LAI, Chengjung; QIAN, Changgeng Patent: WO2011/130628 A1, 2011 ; WO 2011/130628 A1

879008-23-8 ~% 603965-77-1

文献：CURIS, INC.; BAO, Rudi; LAI, Chengjung; QIAN, Changgeng Patent: WO2011/130628 A1, 2011 ; WO 2011/130628 A1

148550-51-0 ~% 603965-77-1

文献：Zhang, Zaihui; Sun, Shaoyi; Kodumuru, Vishnumurthy; Hou, Duanjie; Liu, Shifeng; Chakka, Nagasree; Sviridov, Serguei; Chowdhury, Sultan; McLaren, David G.; Ratkay, Leslie G.; Khakh, Kuldip; Cheng, Xing; Gschwend, Heinz W.; Kamboj, Rajender; Fu, Jianmin; Winther, Michael D. Journal of Medicinal Chemistry, 2013 , vol. 56, # 2 p. 568 - 583

2974-30-3 ~% 603965-77-1

文献：Curis, Inc.; Bao, Rudi; Lai, Chengjung; Qian, Changgeng Patent: US2013/102595 A1, 2013 ;

89793-12-4 ~% 603965-77-1

文献：Genetech, Inc.; Curis, Inc.; Cai, Xiong; Qian, Changgeng; Zhai, Haixiao Patent: US2014/18368 A1, 2014 ;

上下游产品

上游产品  9
110-85-0 89793-12-4 253315-69-4 763-69-9
33458-27-4 95928-49-7 879008-23-8 148550-51-0
2974-30-3
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%