4295-63-0

• 常用中文名：美普替索
• 常用英文名：9-[3-(dimethylamino)propyl]-2-methoxythioxanthen-9-ol
• CAS号：4295-63-0
• 分子式：C₁₉H₂₃NO₂S
• 分子量：329.45600
• 发布时间：2018-09-30 00:27:25
• 更新时间：2024-01-03 19:42:32

名称

• 中文名: 美普替索
• 英文名: 9-[3-(dimethylamino)propyl]-2-methoxythioxanthen-9-ol
• 英文别名: 2-Methoxy-10-(3-dimethylamino-propyl)-10-hydroxy-thioxanthen; 2-Methoxy-9-(3-dimethylamino-propyl)-thioxanthen-9-ol; 9-Hydroxy-2-methoxy-9-(3-dimethylamino-propyl)-thioxanthen; Meprotixol; N-7020; Meprotixolum [INN-Latin]; 9-(3-(Dimethylamino)propyl)-2-methoxy-thioxanthene-9-ol; Meprotixol (INN); Meprothixol; 9-(3-dimethylamino-propyl)-2-methoxy-thioxanthen-9-ol

物化性质

• 密度: 1.179 g/cm3
• 沸点: 483.5ºC at 760mmHg
• 分子式: C₁₉H₂₃NO₂S
• 分子量: 329.45600
• 闪点: 246.2ºC
• 精确质量: 329.14500
• PSA: 58.00000
• LogP: 3.73750
• 折射率: 1.611

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XO0750000 CHEMICAL NAME : Thioxanthene, 2-methoxy-9-((3-dimethylamino)propyl)-9-hydroxy- CAS REGISTRY NUMBER : 4295-63-0 BEILSTEIN REFERENCE NO. : 0303367 LAST UPDATED : 199707 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C19-H23-N-O2-S MOLECULAR WEIGHT : 329.49 WISWESSER LINE NOTATION : T C666 BS IHJ FO1 IQ I3N1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 60 mg/kg TOXIC EFFECTS : Behavioral - sleep REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 19,87,1962

合成路线

40478-82-8 120615-47-6 ~% 4295-63-0

文献：Hoffmann-La Roche Patent: DE1044103 , 1957 ;

109-54-6 ~% 4295-63-0

文献：Am. Cyanamid Co. Patent: GB834143 , 1957 ;

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