436-40-8

• 常用中文名：2,5-Cyclohexadiene-1,4-dione,2,5-bis(1-aziridinyl)-3,6-dipropoxy-
• 常用英文名：2,5-Cyclohexadiene-1,4-dione,2,5-bis(1-aziridinyl)-3,6-dipropoxy-
• CAS号：436-40-8
• 分子式：C₁₆H₂₂N₂O₄
• 分子量：306.35700
• 发布时间：2016-12-08 08:31:48
• 更新时间：2025-10-09 12:33:44

名称

• 英文名: 2,5-bis(aziridin-1-yl)-3,6-dipropoxycyclohexa-2,5-diene-1,4-dione
• 英文别名: Bayer E 39; 2,5-bis-aziridin-1-yl-3,6-dipropoxy-[1,4]benzoquinone; 2,5-Bis-aziridin-1-yl-3,6-dipropoxy-[1,4]benzochinon; Cytostaticum; Improcuona [INN-Spanish]; Zytostatika; Inprochonum; Inproquonum [INN-Latin]; Cytostatika; 2.5-Bis-<aziridinyl-(1)>-3.6-di-propyloxy-benzochinon-(1.4); Inproquone; E 39; RP 6870

物化性质

• 分子式: C₁₆H₂₂N₂O₄
• 分子量: 306.35700
• 精确质量: 306.15800
• PSA: 58.62000
• LogP: 0.92160

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DK3327000 CHEMICAL NAME : p-Benzoquinone, 2,5-bis(1-aziridinyl)-3,6-dipropoxy- CAS REGISTRY NUMBER : 436-40-8 BEILSTEIN REFERENCE NO. : 0286633 LAST UPDATED : 199612 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C16-H22-N2-O4 MOLECULAR WEIGHT : 306.40 WISWESSER LINE NOTATION : T3NTJ A- BL6V DVJ CO3 FO3 E- AT3NTJ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4300 ug/kg TOXIC EFFECTS : Gastrointestinal - hypermotility, diarrhea Blood - hemorrhage Nutritional and Gross Metabolic - other changes TYPE OF TEST : Sex chromosome loss and nondisjunction TYPE OF TEST : Cytogenetic analysis TYPE OF TEST : Sister chromatid exchange MUTATION DATA TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Cells - not otherwise specified DOSE/DURATION : 290 nmol/L REFERENCE : SOGEBZ Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966- Volume(issue)/page/year: 18,210,1982

安全

• 海关编码: 2933990090

合成路线

7251-14-1 6819-41-6 ~% 436-40-8

文献：Farbenfabr. Bayer Patent: DE943166 , 1954 ; Full Text Show Details Lidaks et al. Latvijas PSR Zinatnu Akademijas Vestis, 1959 , # 1 p. 87,88 Chem.Abstr., 1959 , p. 17991 Full Text Show Details Petersen et al. Angewandte Chemie, 1955 , vol. 67, p. 217,219

57998-73-9 6819-41-6 ~% 436-40-8

文献：Farbenfabr. Bayer Patent: DE943166 , 1954 ; Full Text Show Details Lidaks et al. Latvijas PSR Zinatnu Akademijas Vestis, 1959 , # 1 p. 87,88 Chem.Abstr., 1959 , p. 17991 Full Text Show Details Petersen et al. Angewandte Chemie, 1955 , vol. 67, p. 217,219

488-48-2 ~% 436-40-8

文献：Petersen et al. Angewandte Chemie, 1955 , vol. 67, p. 217,219

118-75-2 ~% 436-40-8

文献：Petersen et al. Angewandte Chemie, 1955 , vol. 67, p. 217,219

上下游产品

上游产品  5
7251-14-1 6819-41-6 57998-73-9 488-48-2
118-75-2
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%