83903-06-4

• 常用中文名：鲁匹替丁
• 常用英文名：Lupitidine
• CAS号：83903-06-4
• 分子式：C₂₁H₂₇N₅O₂S
• 分子量：413.53600
• 发布时间：2018-04-30 08:00:00
• 更新时间：2024-01-12 11:53:44

名称

• 中文名: 鲁匹替丁
• 英文名: 2-[2-[[5-(2-aminopropan-2-yl)furan-2-yl]methylsulfanyl]ethylamino]-5-[(6-methylpyridin-3-yl)methyl]-1H-pyrimidin-6-one
• 英文别名: 2-[2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-(6-methyl-3-pyridylmethyl)-4-pyrimidone; LUPITIDINE; Lupitidine [INN]; 2-[2-(5-dimethylaminomethyl-furan-2-ylmethylthio)ethylamino]-5-(6-methyl-pyridin-3-ylmethyl)-4-pyrimidone; Lupitidinum; 2-[[2-[[[5-[(dimethylamino)methyl]-furan-2-yl]methyl]thio]ethyl]amino]-5-(6-methyl-3-pyridinyl)methyl-4(1H)-pyrimidinone; UNII-WF028DWK9N; Lupitidinum [Latin]; 2[2-(5-dimethylaminomethyl-2-furylmethylthio)-ethylamino]-5-(6-methyl-3-pyridylmethyl)-4-pyrimidinone; 2-[2-(5-dimethylaminomethyl-2-furanylmethylthio)ethylamino]-5-(6-methyl-pyridin-3-ylmethyl)-4-pyrimidone

物化性质

• 密度: 1.25g/cm3
• 沸点: 559.4ºC at 760 mmHg
• 分子式: C₂₁H₂₇N₅O₂S
• 分子量: 413.53600
• 闪点: 292.1ºC
• 精确质量: 413.18900
• PSA: 112.35000
• LogP: 3.13700
• 折射率: 1.629

合成路线

36415-21-1 ~% 83903-06-4

文献：Brown; Armitage; Blakemore; Blurton; Durant; Ganellin; Ife; Parsons; Rawlings; Slingsby European Journal of Medicinal Chemistry, 1990 , vol. 25, # 3 p. 217 - 226

72716-93-9 ~% 83903-06-4

文献：Brown; Armitage; Blakemore; Blurton; Durant; Ganellin; Ife; Parsons; Rawlings; Slingsby European Journal of Medicinal Chemistry, 1990 , vol. 25, # 3 p. 217 - 226

66356-53-4 71351-50-3 ~% 83903-06-4

文献：Brown; Armitage; Blakemore; Blurton; Durant; Ganellin; Ife; Parsons; Rawlings; Slingsby European Journal of Medicinal Chemistry, 1990 , vol. 25, # 3 p. 217 - 226

66356-53-4 72716-93-9 ~% 83903-06-4

文献：Brown; Armitage; Blakemore; Blurton; Durant; Ganellin; Ife; Parsons; Rawlings; Slingsby European Journal of Medicinal Chemistry, 1990 , vol. 25, # 3 p. 217 - 226

50-00-0 72717-05-6 124-40-3 ~% 83903-06-4

文献：Brown; Armitage; Blakemore; Blurton; Durant; Ganellin; Ife; Parsons; Rawlings; Slingsby European Journal of Medicinal Chemistry, 1990 , vol. 25, # 3 p. 217 - 226

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36415-21-1 72716-93-9 66356-53-4 71351-50-3
50-00-0 72717-05-6 124-40-3
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