578-07-4

• 常用中文名：吖啶-4-胺
• 常用英文名：Acridin-4-amine
• CAS号：578-07-4
• 分子式：C₁₃H₁₀N₂
• 分子量：194.23200
• 发布时间：2018-07-17 12:42:50
• 更新时间：2025-08-25 15:45:15

名称

• 中文名: 5-氨基吖啶
• 英文名: 4-aminoacridine
• 中文别名: 4-氨基啶
• 英文别名: 4-amino-acridin; 4-aminoakridin; Acridine-5-amine; acridin-4-ylamine; 4-acridinamine; Acridin-4-amine

物化性质

• 密度: 1.268 g/cm3
• 沸点: 419.8ºC at 760 mmHg
• 熔点: 241ºC
• 分子式: C₁₃H₁₀N₂
• 分子量: 194.23200
• 闪点: 237.2ºC
• 精确质量: 194.08400
• PSA: 38.91000
• LogP: 3.55140
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AR7270000 CHEMICAL NAME : Acridine, 4-amino- CAS REGISTRY NUMBER : 578-07-4 BEILSTEIN REFERENCE NO. : 0142257 LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C13-H10-N2 MOLECULAR WEIGHT : 194.25 WISWESSER LINE NOTATION : T C666 BNJ DZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 910 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Yeast - Saccharomyces cerevisiae DOSE/DURATION : 2 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 4,289,1967

合成路线

872-50-4 18123-20-1 7462-74-0 ~% 578-07-4

文献：Aventis Pharmaceuticals Inc. Patent: EP944600 B1, 2002 ;

42955-73-7 ~% 578-07-4

文献：Lehmstedt Chemische Berichte, 1927 , vol. 60, p. 1370 Chemische Berichte, 1931 , vol. 64, p. 2383

18123-20-1 ~% 578-07-4

文献：Weidner, John J.; Peet, Norton P. Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 6 p. 1857 - 1860

4261-62-5 ~% 578-07-4

文献：Albert; Ritchie Journal of the Society of Chemical Industry, London, 1941 , vol. 60, p. 121,122 Organic Syntheses, 1942 , vol. 22, p. 6

71-41-0 81104-13-4 ~% 578-07-4

文献：Ullmann; Maag Chemische Berichte, 1907 , vol. 40, p. 2522

上下游产品

上游产品  7
872-50-4 18123-20-1 7462-74-0 42955-73-7
4261-62-5 71-41-0 81104-13-4
下游产品  1
18123-20-1