1671-82-5

• 常用中文名：1-甲基-2-硝基-1H-咪唑
• 常用英文名：1H-Imidazole,1-methyl-2-nitro-
• CAS号：1671-82-5
• 分子式：C₄H₅N₃O₂
• 分子量：127.10100
• 发布时间：2018-09-08 19:26:08
• 更新时间：2025-08-25 16:22:08

名称

• 中文名: 1-甲基-2-硝基-1H-咪唑
• 英文名: 1-methyl-2-nitroimidazole
• 英文别名: 1-METHYL-2-NITRO-1H-IMIDAZOLE; 1H-Imidazole,1-methyl-2-nitro; Imidazole,1-methyl-2-nitro

物化性质

• 密度: 1.44g/cm3
• 沸点: 308.9ºC at 760mmHg
• 分子式: C₄H₅N₃O₂
• 分子量: 127.10100
• 闪点: 140.6ºC
• 精确质量: 127.03800
• PSA: 63.64000
• LogP: 0.85150
• 蒸汽压: 0.000662mmHg at 25°C
• 折射率: 1.618
• 储存条件: 2-8°C，干燥密封

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NI7500000 CHEMICAL NAME : Imidazole, 1-methyl-2-nitro- CAS REGISTRY NUMBER : 1671-82-5 BEILSTEIN REFERENCE NO. : 0607942 LAST UPDATED : 199612 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C4-H5-N3-O2 MOLECULAR WEIGHT : 127.12 WISWESSER LINE NOTATION : T5N CNJ A1 BNW HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 126 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 126 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 158 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 5 umol/L REFERENCE : BJCSB5 British Journal of Cancer, Supplement. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2ZS, UK) No.1- 1973- Volume(issue)/page/year: 3,60,1978 *** REVIEWS *** TOXICOLOGY REVIEW ADCMAZ Advances in Chemotherapy. (New York, NY) V.1-3, 1964-68. For publisher information, see AVPCAQ. Volume(issue)/page/year: 3,39,1968

合成路线

616-47-7 ~5% 5213-50-3 19183-20-1 1671-82-5

文献：US7304164 B1, ; Page/Page column 7 ;

527-73-1 77-78-1 ~37% 1671-82-5

文献：New Journal of Chemistry, , vol. 30, # 3 p. 349 - 358

616-47-7 ~0% 3034-41-1 5213-50-3 19183-20-1 详细

文献：US7304164 B1, ; Page/Page column 7 ;

616-47-7 ~5% 19183-20-1 1671-82-5 19183-15-4

文献：Synthesis, , # 17 art. no. M43211SS, p. 2859 - 2864

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