26279-89-0

• 常用中文名：Acetamide,2-chloro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
• 常用英文名：Acetamide,2-chloro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
• CAS号：26279-89-0
• 分子式：C₂₂H₂₄ClNO₆
• 分子量：433.88200
• 发布时间：2016-11-17 17:53:09
• 更新时间：2024-01-26 12:00:03

名称

• 英文名: 2-chloro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
• 英文别名: 17-Chlorocolchicine; COLCHICINE,17-CHLORO; Chlorcolchicine; Chlorocolchicine

物化性质

• 密度: 1.31g/cm3
• 沸点: 746.3ºC at 760mmHg
• 分子式: C₂₂H₂₄ClNO₆
• 分子量: 433.88200
• 闪点: 405.1ºC
• 精确质量: 433.12900
• PSA: 83.09000
• LogP: 3.48140
• 蒸汽压: 3.8E-22mmHg at 25°C
• 折射率: 1.591

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GH0740000 CHEMICAL NAME : Colchicine, 17-chloro- CAS REGISTRY NUMBER : 26279-89-0 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C22-H24-Cl-N-O6 MOLECULAR WEIGHT : 433.92 WISWESSER LINE NOTATION : L B677 MV&T&J CO1 DO1 EO1 JMV1G NO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1251 ug/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981