968-58-1

• 常用中文名：alpha,alpha-diphenylpiperidine-1-propanol hydrochloride
• 常用英文名：alpha,alpha-diphenylpiperidine-1-propanol hydrochloride
• CAS号：968-58-1
• 分子式：C₂₀H₂₆ClNO
• 分子量：331.88000
• 发布时间：2017-12-30 00:00:11
• 更新时间：2024-03-01 17:59:56

名称

• 英文名: 1,1-diphenyl-3-piperidin-1-ylpropan-1-ol,hydrochloride
• 英文别名: Mitanoline; 1,1-diphenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride(1:1); 3-Piperidino-1,1-diphenyl-1-propanol hydrochloride; 1,1-diphenyl-3-piperidino-propan-1-ol,hydrochloride; Pridinol hydrochloride; Pridinol-hydrochlorid; EINECS 213-529-9; Par KS-12; 1,1-Diphenyl-3-piperidino-propan-1-ol,Hydrochlorid; 1,1-Diphenyl-3-piperidino-1-propanol hydrochloride

物化性质

• 密度: 1.079g/cm3
• 沸点: 460.9ºC at 760mmHg
• 熔点: 120-121ºC
• 分子式: C₂₀H₂₆ClNO
• 分子量: 331.88000
• 闪点: 229.9ºC
• 精确质量: 331.17000
• PSA: 23.47000
• LogP: 4.53840

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TN2856000 CHEMICAL NAME : 1-Piperidinepropanol, alpha,alpha-diphenyl-, hydrochloride CAS REGISTRY NUMBER : 968-58-1 LAST UPDATED : 199606 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C20-H25-N-O.Cl-H MOLECULAR WEIGHT : 331.92 WISWESSER LINE NOTATION : T6NTJ A2XQR&R &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 91 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 33 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 131 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 25 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 116,177,1956 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1500 mg/kg/15W-I TOXIC EFFECTS : Behavioral - irritability REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949

安全

• 海关编码: 2933399090

合成路线

110-89-4 ~% 968-58-1

文献：Dar; Thiruvazhi; Abraham; Kitayama; Kopajtic; Gamliel; Slusher; Carroll; Uhl European Journal of Medicinal Chemistry, 2005 , vol. 40, # 10 p. 1013 - 1021

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海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%