55314-49-3

• 常用中文名：Prostaglandin F2α 1,15-lactone
• 常用英文名：Prostaglandin F2α 1,15-lactone (PGF2α 1,15-lactone)
• CAS号：55314-49-3
• 分子式：C₂₀H₃₂O₄
• 分子量：336.466
• 发布时间：2016-06-23 19:24:45
• 更新时间：2024-01-13 19:12:55
• PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α.

名称

• 中文名: 前列腺素F2α1,15-内酯
• 英文名: 9alpha, 11alpha, 15s-trihydroxy-prosta-5z, 13e-dien-1-oic acid, 1,15-lactone
• 英文别名: pgf2-alpha1,15-lactone; Prosta-5,13-dien-1-one, 1,15-epoxy-9,11-dihydroxy-, (5Z,9α,11α,13E,15S)-; (5Z,9α,11α,13E,15S)-9,11-Dihydroxy-1,15-epoxyprosta-5,13-dien-1-one; 13e,15s)-1-alph; PROSTAGLANDIN F2ALPHA 1,15-LACTONE

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 524.1±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₂O₄
• 分子量: 336.466
• 闪点: 180.9±23.6 °C
• 精确质量: 336.230072
• PSA: 66.76000
• LogP: 3.09
• 蒸汽压: 0.0±3.1 mmHg at 25°C
• 折射率: 1.503
• 储存条件: -20°C，密闭，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UK8020600 CHEMICAL NAME : Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, lambda-lactone, (5Z,9-alpha,11-alpha, 13E,15S)- CAS REGISTRY NUMBER : 55314-49-3 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H32-O4 MOLECULAR WEIGHT : 336.52 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular DOSE : 4 mg/kg SEX/DURATION : female 1 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - menstrual cycle changes or disorders REFERENCE : PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 14,477,1977 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 800 ug/kg SEX/DURATION : female 4 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1089,1983

合成路线

62410-92-8 ~% 55314-49-3

文献：Bundy; Peterson; Cornette; Miller; Spilman; Wilks Journal of Medicinal Chemistry, 1983 , vol. 26, # 8 p. 1089 - 1099

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