405169-01-9

• 常用中文名：4-Amino-3-(1H-benzimidazol-2-yl)-5-(4-methyl-1-piperazinyl)-2(1H) -quinolinone
• 常用英文名：4-Amino-3-(1H-benzimidazol-2-yl)-5-(4-methyl-1-piperazinyl)-2(1H) -quinolinone
• CAS号：405169-01-9
• 分子式：C₂₁H₂₂N₆O
• 分子量：374.43900
• 发布时间：2018-06-21 18:08:16
• 更新时间：2024-01-30 12:00:02

名称

• 英文名: 4-Amino-3-(1H-benzimidazol-2-yl)-5-(4-methyl-1-piperazinyl)-2(1H) -quinolinone
• 英文别名: 4-amino-2-trifluoromethyl-pyrimidine-5-carbonitrile; 4-Amino-2-trifluormethyl-pyrimidin-5-carbonitril; 2-trifluoromethyl-5-cyano-6-aminopyrimidine

物化性质

• 分子式: C₂₁H₂₂N₆O
• 分子量: 374.43900
• 精确质量: 374.18600
• PSA: 94.30000
• LogP: 3.40180

合成路线

14741-71-0 63365-17-3 ~14% 405169-01-9

文献：Renhowe, Paul A.; Pecchi, Sabina; Shafer, Cynthia M.; Machajewski, Timothy D.; Jazan, Elisa M.; Taylor, Clarke; Antonios-McCrea, William; McBride, Christopher M.; Frazier, Kelly; Wiesmann, Marion; Lapointe, Gena R.; Feucht, Paul H.; Warne, Robert L.; Heise, Carla C.; Menezes, Daniel; Aardalen, Kimberly; Ye, Helen; He, Molly; Le, Vincent; Vora, Jayesh; Jansen, Johanna M.; Wernette-Hammond, Mary Ellen; Harris, Alex L. Journal of Medicinal Chemistry, 2009 , vol. 52, # 2 p. 278 - 292