87295-93-0

• 常用中文名：4-(Dimethylamino)-3-((dimethylamino)methylene)-1,3-dihydro-2H-1,5-benz odiazepin-2-one
• 常用英文名：4-(Dimethylamino)-3-((dimethylamino)methylene)-1,3-dihydro-2H-1,5-benz odiazepin-2-one
• CAS号：87295-93-0
• 分子式：C₁₄H₁₈N₄O
• 分子量：258.31900
• 发布时间：2017-10-17 10:46:02
• 更新时间：2024-01-14 22:37:13

名称

• 英文名: (3Z)-4-(Dimethylamino)-3-[(dimethylamino)methylene]-1,3-dihydro-2 H-1,5-benzodiazepin-2-one
• 英文别名: N,N-Dimethyl-N'-oxidiethylen-thiocarbamoylsulfenamid; Dimethylthiocarbamoylsulfen-saeuremorpholid; Morpholine,4-[[(dimethylamino)thioxomethyl]thio]; N-(N,N-dimethylthiocarbamoyldithioyl)morpholine; (dimethylamino)morpholin-4-ylthiomethane-1-thione; Dithiocarbamic acid,N,N-dimethyl-,S-(4-morpholyl) ester; 4-(dimetilammino)-3-<(dimetilammino)metilen>-1,3-diidro-2H-1,5-benzodiazepin-2-one; Dimethylthiocarbamoyl-morpholino-sulfan; 4-(dimethyl-thiocarbamoylsulfanyl)-morpholine

物化性质

• 密度: 1.14g/cm3
• 分子式: C₁₄H₁₈N₄O
• 分子量: 258.31900
• 精确质量: 258.14800
• PSA: 51.43000
• LogP: 1.19650
• 折射率: 1.589

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DF2378200 CHEMICAL NAME : 2H-1,5-Benzodiazepin-2-one, 1,3-dihydro-4-(dimethylamino)-3-((dimethylamino)methy lene)- CAS REGISTRY NUMBER : 87295-93-0 LAST UPDATED : 199306 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C14-H18-N4-O MOLECULAR WEIGHT : 258.36 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 38,546,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 38,546,1983

合成路线

68-12-2 62537-60-4 ~38% 87295-93-0

文献：Roma; Balbi; Ermili; Vigevani Farmaco, Edizione Scientifica, 1983 , vol. 38, # 8 p. 546 - 558